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Evaluation of Calorimetric and Gravimetric Methods to Quantify the Amorphous Content of Desferal

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Abstract

The amorphous content of different Desferal samples was quantified by recording its recrystallization using isothermal microcalorimetry in a static as well as in a flowing humid atmosphere. Furthermore water vapor sorption gravimetry was performed for the same purpose. These analytical methods result in a quantitative signal directly dependent on the content of the amorphous phase (recrystallization, water sorption equilibrium). Their sensitivity allows the detection of amorphous content below 1%. Methods are compared and advantages and disadvantages are discussed.

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Authors
  1. K. Fiebich
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  2. M. Mutz
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Fiebich, K., Mutz, M. Evaluation of Calorimetric and Gravimetric Methods to Quantify the Amorphous Content of Desferal. Journal of Thermal Analysis and Calorimetry 57, 75–85 (1999). https://doi.org/10.1023/A:1010153401365

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  • DOI: https://doi.org/10.1023/A:1010153401365

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