Abstract
As part of the investigation on useful constituents in microalgae, we searched for angiotensin converting enzyme inhibitory activities in water-soluble and fat-soluble fractions of sixteen species and strains. Water-soluble fractions of eleven species and fat-soluble fractions of eight species showed inhibitory activities. In particular, the water-soluble fractions of the freshwater cyanophytesMicrocystis spp. showed inhibition at a concentration as low as 0.25 mg ml−1, and that of the halotolerant chlorophyteDunaliella bardawil showed moderate inhibition. The active principles were suggested to be low molecular peptides.
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Yamaguchi, K., Murakami, M. & Okino, T. Screening of angiotensin-converting enzyme inhibitory activities in microalgae. J Appl Phycol 1, 271–275 (1989). https://doi.org/10.1007/BF00003653
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DOI: https://doi.org/10.1007/BF00003653