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Calcium-binding proteins and development

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Abstract

The known roles for calcium-binding proteins in developmental signaling pathways are reviewed. Current information on the calcium-binding characteristics of three classes of cell-surface developmental signaling proteins (EGF-domain proteins, cadherins and integrins) is presented together with an overview of the intra-cellular pathways downstream of these surface receptors. The developmental roles delineated to date for the universal intracellular calcium sensor, calmodulin, and its targets, and for calcium-binding regulators of the cytoskeleton are also reviewed.© Kluwer Academic Publishers

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Beckingham, K., Qing Lu, A. & Andruss, B.F. Calcium-binding proteins and development. Biometals 11, 359–372 (1998). https://doi.org/10.1023/A:1009201824806

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