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Synthesis of chloromethylphosphine oxides

  • Organic Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    We have developed a method for the preparation of chloromethylphosphine oxides by substitution of the acetoxy group in acetoxymethylphosphine oxides by chlorine using gaseous HC1 at 180–200°C.

  2. 2.

    We have prepared methylbis(chloromethyl)phosphine oxide by reaction of gaseous HC1 with tris(acetoxymethyl)phosphine or tetrakis(hydroxymethyl)phosphonium chloride. In the same way we synthesized dimethylchloromethylphosphine oxide from tris(hydroxymethyl)phosphine methylsulfate.

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Authors and Affiliations

  1. Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, Moscow

    E. N. Tsvetkov, T. E. Kron & M. I. Kabachnik

Authors
  1. E. N. Tsvetkov
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  2. T. E. Kron
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  3. M. I. Kabachnik
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 669–672, March, 1980.

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Tsvetkov, E.N., Kron, T.E. & Kabachnik, M.I. Synthesis of chloromethylphosphine oxides. Russ Chem Bull 29, 491–494 (1980). https://doi.org/10.1007/BF00949641

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  • DOI: https://doi.org/10.1007/BF00949641

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