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Products of the reaction of 2-chloro-6-thio-7-methyl-purine with amines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Treatment of 2-chloro-6-thio-7-methylpurine with aniline, piperidine, or morpholine with heating in DMF gives 2-phenylamino(piperidino or morpholino)-6-thio-7-methylpurine. The scheme for the formation of the side products 2,6-dithio-and 2,6-dipiperidino-7-methylpurine is discussed.

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Authors and Affiliations

  1. Center for the Chemistry of Medicnal Compounds, All Russian Chemico-Pharmaceutical Science Research Institute, 119815, Moscow

    P. M. Kochergin & V. S. Korsunskii

  2. Zaporozh'ye State Medicinal University, 330074, Zaporozh'ye, Ukraine

    E. V. Aleksandrova

Authors
  1. P. M. Kochergin
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  2. E. V. Aleksandrova
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  3. V. S. Korsunskii
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 82–84, January, 2000.

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Kochergin, P.M., Aleksandrova, E.V. & Korsunskii, V.S. Products of the reaction of 2-chloro-6-thio-7-methyl-purine with amines. Chem Heterocycl Compd 36, 74–76 (2000). https://doi.org/10.1007/BF02256849

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  • DOI: https://doi.org/10.1007/BF02256849

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