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The surface modification of polymers to modulate endothelial cell growth

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The effect of nitrogen ion implantation or ion-assisted film deposition on the growth of human endothelial cells in vitro on a substrate has been studied. It was shown that the largest change occurs when TiO2 films were reactively sputtered onto the substrates, while the most passive surface was reactively sputtered SiO2. SEM pictures of the cells adhering to the various treated surfaces show that the cells were healthy. Future studies on the effect of alloy films and their oxides and nitrides are proposed.

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Authors and Affiliations

  1. Centre for Thin Film and Surface Research, The University of Salford, M5 4WT, Salford, UK

    J. S. Colligon

  2. Institute of Pathology, Aachen University of Technology, D-52057, Aachen, Germany

    A. Dekker

  3. Public Health Laboratory, Withington Hospital, M20 2LR, Manchester, UK

    A. Curry

  4. Institute of Pathology, Johannes Gutenberg University, D-55101, Mainz, Germany

    C. J. Kirkpatrick

Authors
  1. J. S. Colligon
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  2. A. Dekker
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  3. A. Curry
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  4. C. J. Kirkpatrick
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Colligon, J.S., Dekker, A., Curry, A. et al. The surface modification of polymers to modulate endothelial cell growth. J Mater Sci: Mater Med 7, 119–123 (1996). https://doi.org/10.1007/BF00058723

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  • DOI: https://doi.org/10.1007/BF00058723

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