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Comparison of diurnal and nocturnal rates of 5-hydroxytryptamine turnover in the rat mediobasal hypothalamus

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Summary

Rates of 5-hydroxytryptamine (5-HT) turnover in the mediobasal hypothalamus of male rats were estimated using pharmacological methods during the daytime and at night. Concentrations of 5-HT in this hypothalamic area were higher nocturnally than diurnally; this was apparently due to increased 5-HT synthesis and decreased 5-HT catabolism at night.

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References

  1. For review, see: Müller, E.E., Nisticó, G., and Scapagnini U., Neurotransmitters and anterior pituitary function. Academic Press, New York 1977.

    Google Scholar 

  2. Scapagnini, U., Moberg, G.P., VanLoon, G. R., deGroot, J., and Ganong, W. F., Neuroendocrinology7 (1971) 90.

    Article  CAS  PubMed  Google Scholar 

  3. Quay, W.B., Am. J. Physiol.215 (1968) 1448.

    Article  CAS  PubMed  Google Scholar 

  4. Krieger, D.T., Neuroendocrinology17 (1975) 62.

    Article  CAS  PubMed  Google Scholar 

  5. Asano, Y., Life Sci.10 (1971) 883.

    Article  CAS  Google Scholar 

  6. Matsumoto, M., Kimura, K., Fujisawa, A., Uyama, O., Yoneda, S., Imaizumi, M., Wada, H., and Abe, H., J. Neurochem.37 (1981) 792.

    CAS  PubMed  Google Scholar 

  7. Bucht, G., Adlofsson, R., Gottfries, C.G., Roos, B.-E., and Winblad, B., J. neural Transm.51 (1981) 185.

    Article  CAS  PubMed  Google Scholar 

  8. Neff, N.H., and Tozer, T.N., Adv. Pharmac.6A (1968) 97.

    Article  Google Scholar 

  9. Héry, M., Faudon, M., Dusticier, G., and Héry, F., J. Endocr.94 (1982) 157.

    Article  PubMed  Google Scholar 

  10. Héry, F., Rover, E., and Glowinsky, J., Brain Res.43 (1972) 445.

    Article  PubMed  Google Scholar 

  11. Costa, E., and Neff, N.H., in: Handbook of Neurochemistry, Ed. A. Lajtha. Plenum Press, New York 1970.

    Google Scholar 

  12. Steger, R.W., DePaulo, L., Asch, R.H., and Silverman, A.Y., Neuroendocrinology37 (1983) 361.

    Article  CAS  PubMed  Google Scholar 

  13. Selmanoff, M., and Wise, P.M., Brain Res.212 (1981) 101.

    Article  CAS  PubMed  Google Scholar 

  14. Gal, E.M., Brain Res.44 (1972) 309.

    Article  CAS  PubMed  Google Scholar 

  15. Carlsson, A., Kehr, W., and Lindqvist, M., J. neural Transm.39 (1976) 1.

    Article  CAS  PubMed  Google Scholar 

  16. Burkard, W.P., Gey, K.F., and Pletscher, A., Archs Biochem.107 (1964) 187.

    Article  CAS  Google Scholar 

  17. Carlsson, A., and Lindqvist, M., J. neural Transm.34 (1973) 79.

    Article  CAS  PubMed  Google Scholar 

  18. Carlsson, A., and Lindqvist, M., J. neural Transm.39 (1976) 1.

    Article  CAS  PubMed  Google Scholar 

  19. Tozer, T.N., Neff, N.H., and Brodie, B.B., J. Pharmac. exp. Ther.153 (1966) 177.

    CAS  Google Scholar 

  20. Lane, J.D., and Aprison, M.H., J. Neurochem.30 (1978) 671.

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Departments of Cellular and Structural Biology and Obstetrics-Gynecology, The University of Texas Health Science Center, 78284, San Antonio, Texas, USA

    T. S. King, S. Steinlechner & R. W. Steger

  2. Fachbereich Biologie der Philipps-Universität, Zoologie, D-3550, Marburg, Federal Republic of Germany

    T. S. King, S. Steinlechner & R. W. Steger

Authors
  1. T. S. King
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  2. S. Steinlechner
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  3. R. W. Steger
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Additional information

Supported by NIH grant RR07187 (TSK) and NIH grant HD10202 (Neuroendocrine Core).

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King, T.S., Steinlechner, S. & Steger, R.W. Comparison of diurnal and nocturnal rates of 5-hydroxytryptamine turnover in the rat mediobasal hypothalamus. Experientia 41, 417–419 (1985). https://doi.org/10.1007/BF02004536

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  • DOI: https://doi.org/10.1007/BF02004536

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