Summary
The synthesis of 3 polypeptides with molecular weights of 103-, 80- and 78-kdalton (K) was dramatically accelerated when the cultures of human embryonic fibroblasts were transferred from 37 to 40°C. The induction of these polypeptides was not observed if actinomycin D was added to the cultures at the beginning of the rising of the temperature, indicating that this response may be mediated by increased transcription of their messenger RNA.
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Nishiyama, Y., Tsutsui, Y., Tsurumi, T. et al. Heat(40°C)-induced polypeptides in human embryonic fibroblasts. Experientia 39, 412–413 (1983). https://doi.org/10.1007/BF01963154
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DOI: https://doi.org/10.1007/BF01963154