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Inhibition of DNA synthesis in erythroleukemic cells by a liver protein fraction

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Summary

The liver inhibitory factor (LIF) extracted inhibits in vitro the proliferation of erythroleukemic cells. This inhibition takes place 24 h after LIF treatment and is promptly reversible on removal of the factor.3H-thymidine autoradiography shows that the effect is probably due to a blockage of the cells at the end of G1.

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References

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Authors and Affiliations

  1. Istituto di Patologia Generale, Facoltà di Medicina e Chirurgia, Policlinico Monteluce, I-06100, Perugia, Italia

    M. P. Viola-Magni & P. Ricerchi

Authors
  1. M. P. Viola-Magni
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  2. P. Ricerchi
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Viola-Magni, M.P., Ricerchi, P. Inhibition of DNA synthesis in erythroleukemic cells by a liver protein fraction. Experientia 39, 180–182 (1983). https://doi.org/10.1007/BF01958888

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  • DOI: https://doi.org/10.1007/BF01958888

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