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Demonstration of tissue-specific antigens shared by normal pancreas and pancreatic neoplasms

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Summary

Xenoantiserum raised against extracts of normal hamster pancreas, after absorption with normal tissues, reacted specifically with normal hamster and human pancreas by immunodiffusion. Absorbed antiserum also reacted with hamster and human pancreatic carcinoma but not with other neoplasms. Immunization of hamsters with normal pancreas extracts prevented growth of transplantable pancreatic carcinomas.

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Refences

  1. Rose, N.R., Metzgar, R.S., and Witebsky, E., J. Immun.85 (1960) 575.

    Article  CAS  PubMed  Google Scholar 

  2. Metzgar, R.S., J. Immun.93 (1964) 176.

    Article  CAS  PubMed  Google Scholar 

  3. Metzgar, R.S., Nature203 (1964) 660.

    Article  CAS  PubMed  Google Scholar 

  4. Metzgar, R.S., Transplantn Proc.12 (1980) suppl. 1, 123.

    CAS  Google Scholar 

  5. Pour, P., Krüger, F.W., Althoff, J., Cardesa, A., and Mohr, U., Am. J. Path.76 (1974) 349.

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Pour, P., Mohr, U., Cardesa, A., Althoff, J., and Krüger, F.W., Cancer36 (1975) 379.

    Article  CAS  PubMed  Google Scholar 

  7. Pour, P., Althoff, J., Krüger, F.W., and Mohr, U., Cancer Lett.2 (1977) 323.

    Article  CAS  PubMed  Google Scholar 

  8. Levitt, M.H., Harris, C.C., Squire, R., Springer, S., Wenk, M., Mollelo, C., Thomas, D., Kingsbury, E., and Newkirk, C., Am. J. Path.88 (1977) 5.

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Scarpelli, D.G., and Rao, M.S., Cancer Res.39 (1979) 452.

    CAS  PubMed  Google Scholar 

  10. Takahashi, M., Runge, R., Donnelly, T., and Pour, P., Cancer Lett.7 (1979) 127.

    Article  CAS  PubMed  Google Scholar 

  11. Sindelar, W.F., and Kurman, C.C., J. natl Cancer Inst.67 (1981) 1093.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Surgery Branch, Clinical Oncology Program, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, 20205, Bethesda, Maryland, USA

    W. F. Sindelar, A. R. Dresdale & N. A. Hadley

Authors
  1. W. F. Sindelar
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  2. A. R. Dresdale
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  3. N. A. Hadley
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Sindelar, W.F., Dresdale, A.R. & Hadley, N.A. Demonstration of tissue-specific antigens shared by normal pancreas and pancreatic neoplasms. Experientia 39, 87–89 (1983). https://doi.org/10.1007/BF01960644

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  • DOI: https://doi.org/10.1007/BF01960644

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