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Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats

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Summary

Androgen-insensitive (tfm) rats possess a nuclear-estrogen binding system in the brain that is similar to that of wild-type control males. In these mutant rats, radiolabeled estradiol was bound predominantly to hypothalamic nuclei and this binding was of limited capacity.

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Authors and Affiliations

  1. Long Island Research Institute, Health Sciences Center, 10T, State University of New York at Stony Brook, 11794, Stony Brook, New York, USA

    Kathie L. Olsen & R. E. Whalen

Authors
  1. Kathie L. Olsen
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  2. R. E. Whalen
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Additional information

This research was supported by grants Nos HD-13957 and HD-14726 from the National Institute of Child Health and Human Development.

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Olsen, K.L., Whalen, R.E. Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats. Experientia 38, 139–140 (1982). https://doi.org/10.1007/BF01944575

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  • DOI: https://doi.org/10.1007/BF01944575

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