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Effect of tryptophan on tyrosinase in relation to vitiligo

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Summary

Tryptophan can inhibit DOPA (3,4-dihydroxy phenylalanine) conversion to melanin both by the enzymatic and the nonenzymatic route. Its role has been studied in relation to vitiligo.

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Acknowledgments. The authors wishes to thank Dr S.C. Bhattacharyya, Bose Institute and Dr A. Sen, Department of Chemistry for their interest in the work.

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Chakraborty, A.K., Chatterjee, A., Chakraborty, C. et al. Effect of tryptophan on tyrosinase in relation to vitiligo. Experientia 36, 920–921 (1980). https://doi.org/10.1007/BF01953793

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