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Effects of intracellular or extracellular application of tetraethylammonium on the action potential in cultured chick embryonic heart muscle cell

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Summary

The effects of tetraethylammonium (TEA) on the action potential in cultured chick embryonic heart muscle cells were investigated. The onset of prolongation of the action potential occurred within 10 min following intracellular iontophoretic application of TEA, but after more than 50 min following extracellular application. These facts suggest that the major site of action of TEA is on the inner surface of the membrane in these cells.

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References

  1. C.M. Armstrong and L. Binstock, J. gen. Physiol.48, 859 (1965).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. C.M. Armstrong and B. Hill, J. gen. Physiol.59, 388 (1972).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. R.D. Keynes, E. Rojas, R.E. Taylor and J. Vergas, J. Physiol. (London)229, 409 (1973).

    Article  CAS  PubMed  Google Scholar 

  4. H. Inomata and C.Y. Kao, J. Physiol. (London)255, 347 (1976).

    Article  CAS  PubMed  Google Scholar 

  5. R. Ochi and H. Nishie, Pflügers Arch.348, 305 (1974).

    Article  CAS  PubMed  Google Scholar 

  6. D. Lehmkuhl and N. Sperelakis, Am. J. Physiol.205, 1213 (1963).

    Article  CAS  PubMed  Google Scholar 

  7. R.L. DeHaan, Devl Biol.16, 216 (1967).

    Article  CAS  Google Scholar 

  8. N. Sperelakis and D. Lehmkuhl, J. gen. Physiol.49, 867 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. G. Isenberg, Nature253, 273 (1975).

    Article  CAS  Google Scholar 

  10. Y. Yamasaki, M. Fujiwara and N. Toda, Jap. J. Pharmac.24, 385 (1974).

    Google Scholar 

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Authors and Affiliations

  1. Department of Applied Physiology, Tohoku University School of Medicine, Seiryo-cho 2-1, 980, Sendai, Japan

    Y. Maruyama, E. Yamashita & H. Inomata

  2. Miyagi College of Education, Aramaki Aoba-mubanchi, 980, Sendai, Japan

    Y. Maruyama, E. Yamashita & H. Inomata

Authors
  1. Y. Maruyama
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  2. E. Yamashita
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  3. H. Inomata
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Maruyama, Y., Yamashita, E. & Inomata, H. Effects of intracellular or extracellular application of tetraethylammonium on the action potential in cultured chick embryonic heart muscle cell. Experientia 36, 557–558 (1980). https://doi.org/10.1007/BF01965798

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  • DOI: https://doi.org/10.1007/BF01965798

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