Skip to main content
SpringerLink
Log in

Amino acid composition and sequence of crinia-angiotensin, an angiotensin II-like endecapeptide from the skin of the Australian frogCrinia georgiana

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Methanol extracts of the skin of the Australian amphibianCrinia georgiana contain large amounts of crinia-angiotensin II, a new angiotensin II-like peptide. This differs sharply from the conventional octapeptide angiotensins II in having attached the tripeptide Ala-Pro-Gly- to the N-terminus, and having an Ile residue substituted for the Val residue at position 6 from the C-terminus. Small amounts of angiotensin-like peptides have been traced, by radioimmunoassay, in skin extracts of some otherCrinia species.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. K. Araki, S. Tachibana, M. Uchiyama, T. Nakajima and T. Yasuhara, Chem. pharm. Bull.23, 3132 (1975).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Istituti di Farmacologia Medica I e III dell'Università di Roma, Città Universitaria, I-00100, Roma, Italy

    V. Erspamer, P. Melchiorri, T. Nakajima, T. Yasuhara & R. Endean

  2. Institute of Pharmaceutical Sciences, School of Medicine, Hiroshima University, Kasumi, Hiroshima, Japan

    V. Erspamer, P. Melchiorri, T. Nakajima, T. Yasuhara & R. Endean

  3. Department of Zoology, University of Queensland, St. Lucia, 4067, Brisbane, Australia

    V. Erspamer, P. Melchiorri, T. Nakajima, T. Yasuhara & R. Endean

Authors
  1. V. Erspamer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Melchiorri
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. Nakajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. Yasuhara
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. Endean
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by grants from the Consiglio Nazionale delle Ricerche, Italy, and from the Ministry of Education, Japan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Erspamer, V., Melchiorri, P., Nakajima, T. et al. Amino acid composition and sequence of crinia-angiotensin, an angiotensin II-like endecapeptide from the skin of the Australian frogCrinia georgiana. Experientia 35, 1132–1133 (1979). https://doi.org/10.1007/BF01963240

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01963240

Keywords

Search

Navigation