Summary
Transmission and scanning electron microscopy indicate that rabbit platelets incubated in protein-poor medium retain their reactivity to shape change-inducing agents such as 5-hydroxytryptamine, adenosine-5′-diphosphate and chlorpromazine. Such platelets may be used as models for drug-membrane interactions, e.g. in neuronal cells.
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Graf, M., Richards, J.G., Colombo, V. et al. Shape change reaction of platelets in protein-free medium: Ultramorphology. Experientia 35, 840–842 (1979). https://doi.org/10.1007/BF01968285
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DOI: https://doi.org/10.1007/BF01968285