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Possible mutagenic activity of saccharin

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Summary

A mutagenic effect of saccharin in Chinese hamsters, using the in vivo SCE test, was observed when massive overdoses were administered; cyclamate was not mutagenic.

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References

  1. Food Chemical News, Nov. 20 (1978).

  2. D.L. Arnold, C.A. Moodie, M.C. Grice, S.M. Charbonnean and I.C. Munro, Toxicology Research Division, Health Protection Branch, Ottawa, Canada, April 1977.

  3. P.G.N. Kramers, Mut. Res.32, 81 (1975).

    Article  CAS  Google Scholar 

  4. S. Wolff, B. Rodin, Science200, 543 (1978).

    Article  CAS  PubMed  Google Scholar 

  5. D.T. Arakaki and W. Schmid, Humangenetik11, 119 (1971).

    CAS  PubMed  Google Scholar 

  6. W. Vogel and Th. Bauknecht, Nature260, 448 (1976).

    Article  CAS  PubMed  Google Scholar 

  7. J.W. Allen and S.A. Latt, Nature260, 449 (1976).

    Article  CAS  PubMed  Google Scholar 

  8. J.W. Allen, C.F. Shuler, R.W. Mendes and S.A. Latt, Cytogenet. Cell Genet.18, 231 (1977).

    Article  CAS  PubMed  Google Scholar 

  9. .W. Renner, Drug Res., in press (1979).

  10. FAO Nutrition Meetings Report Series No. 44A, WHO/Food Add./68.33, 1967.

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Renner, H.W. Possible mutagenic activity of saccharin. Experientia 35, 1364–1365 (1979). https://doi.org/10.1007/BF01964011

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