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Effects of pregnancy on the glucose-induced insulin release from cultivated pancreatic islets of the rat

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Summary

7-day-cultured islets from pregnant Wistar rats released at 5.6 mM glucose significantly more insulin than islets from nonpregnant rats, whereas in vivo this heigthened glucose sensitivity is lost 48 h post partum.

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Authors and Affiliations

  1. Zentralinstitut für Diabetes, Forschung und Behandlung «Gerhardt Katsch», DDR-2201, Karlsburg/Greifswald, German Democratic Republic

    Brigitte Ziegler, M. Ziegler & H. Fiedler

Authors
  1. Brigitte Ziegler
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  2. M. Ziegler
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  3. H. Fiedler
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Additional information

Investigations carried out as a part of the ‘Forschungsprojekt Diabetes mellitus und Fettstoffwechselstörungen’ supported by the Ministry of Health of German Democratic Republic.

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Ziegler, B., Ziegler, M. & Fiedler, H. Effects of pregnancy on the glucose-induced insulin release from cultivated pancreatic islets of the rat. Experientia 34, 138–139 (1978). https://doi.org/10.1007/BF01921949

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