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Dopamine beta-hydroxylase in human synovial fluid

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Summary

Dopamine beta-hydroxylase (DBH) activity has been found in synovial fluid obtained from human knees. The enzyme activity was about 5% of the activity found in the serum of the same control patients. DBH activity in synovial fluid of patients suffering osteoarthritis was 3 times higher.

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We thank for the expert technical assistance of Mr Angel García. We are grateful to Drs S. J. Fidone and A. Sillero for assistance with the manuscript. Supported by a grant from the Galerias Preciados Foundation, Valladolid, Spain.

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Sanchez-Martín, M., García, A.G. Dopamine beta-hydroxylase in human synovial fluid. Experientia 33, 650–652 (1977). https://doi.org/10.1007/BF01946554

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