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Synthese und Eigenschaften von Bromocriptin

Synthesis and properties of bromocriptine

  • Specialia Chimica, Biochimica
  • Published:
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Summary

The bromination of α-ergokryptine, a genuine ergot alkaloid of the peptide type, in position 2 of the indol nucleus to 2-bromo-α-ergokryptine is described. Its transformation to the methanesulfonate led to the prolactin inhibitor bromocriptine-methanesulfonate, Parlodel®.

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References

  1. E. Flückiger und H. R. Wagner, Experientia24, 1130 (1968).

    Article  PubMed  Google Scholar 

  2. F. Troxler und A. Hofmann, Helv. chim. Acta40, 2160 (1957).

    Article  CAS  Google Scholar 

  3. W. Schlientz, R. Brunner, A. Rüegger, B. Berde, E. Stürmer und A. Hofmann, Experientia23, 991 (1967).

    Article  CAS  PubMed  Google Scholar 

  4. P. A. Stadler, St. Guttmann, H. Hauth, R. L. Huguenin, Ed. Sandrin, G. Wersin, H. Willems und A. Hofmann, Helv. chim. Acta52, 1549 (1969).

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Chemische Forschung, Pharma Departement, SANDOZ A.G., CH-4002, Basel, Schweiz

    H. R. Schneider, P. A. Stadler, P. Stütz, F. Troxler & J. Seres

Authors
  1. H. R. Schneider
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  2. P. A. Stadler
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  3. P. Stütz
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  4. F. Troxler
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  5. J. Seres
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Additional information

85. Mitteilung über Mutterkornalkaloide.

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Schneider, H.R., Stadler, P.A., Stütz, P. et al. Synthese und Eigenschaften von Bromocriptin. Experientia 33, 1412–1413 (1977). https://doi.org/10.1007/BF01918774

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  • DOI: https://doi.org/10.1007/BF01918774

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