Summary
Rats can produce glycine from hydroxyproline and vice versa. After the injection, hydroxyproline is rapidly converted into glycine and then incorporated into collagen. Later the labelled amino acids in collagen are hydroxyproline, proline, serine, threonine, alanine, and glutamic acid. We suppose that all these labelled amino acids come from glycine.
Similar content being viewed by others
References
S. H. Jackson andJ. A. Heiniger, Biochim. biophys. Acta381, 358 (1975).
K. I. Kivirikko, Acta physiol. scand. Suppl.60, 219 (1963).
A. Ruiz-Torres andI. Kürten Experientia29, 968 (1973).
M. R. Stetten, J. biol. Chem.153, 113 (1944).
P. M. Gallop, Arch. Biochem.54, 486 (1955).
A. Ruiz-Torres andI. Kürten, Z. Geront.7, 133 (1974).
J. Rosenbloom, Arch. Biochem. Biophys.142, 718 (1971).