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Increased erythrocyte permeability to Li and Na in the spontaneously hypertensive rat

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Summary

Red blood cells incubated in a physiological medium in which Li replaces Na (LiPSS) gain Li in exchange for Na and K. The rate of Li uptake is modestly but significantly increased in the spontaneously hypertensie rat (SHR) at 37°C and at 22°C. The slow rate of Na gain and K loss during cooling at 2°C was about doubled in unmodified whole blood samples from the SHR.

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References

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Authors and Affiliations

  1. Department of Anatomy, Faculty of Medicine, The University of British Columbia, V6T 1W5, Vancouver, B.C., Canada

    S. M. Friedman, M. Nakashima, R. A. McIndoe & C. L. Friedman

Authors
  1. S. M. Friedman
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  2. M. Nakashima
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  3. R. A. McIndoe
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  4. C. L. Friedman
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Additional information

This work was carried out with the aid of a grant from the British Columbia Heart Foundation.

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Friedman, S.M., Nakashima, M., McIndoe, R.A. et al. Increased erythrocyte permeability to Li and Na in the spontaneously hypertensive rat. Experientia 32, 476–478 (1976). https://doi.org/10.1007/BF01920806

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  • DOI: https://doi.org/10.1007/BF01920806

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