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Depletion of heart norepinephrine in experimental acute myocarditis caused byTrypanosoma cruzi

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Summary

The norepinephrine content of the heart was reduced to undetectable values in rats inoculated withTrypanosoma cruzi. This fact indicates a massive involvement of the cardiac postganglionic sympathetic fibres in acute Chagas disease.

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Supported by the Conselho Nacional de Pesquisas of Brazil. For encouragement and criticism we thank Dr.Z. Brener and Dr.C. Chiari, to whom we are also indebted for considerable help given in the parasitological aspects of this reserach. For technical assistance we thank Mr.Rubens Miranda.

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Machado, A.B.M., Machado, C.R.S. & Gomes, C.B. Depletion of heart norepinephrine in experimental acute myocarditis caused byTrypanosoma cruzi. Experientia 31, 1202–1203 (1975). https://doi.org/10.1007/BF02326794

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