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β-Pyrrolo-L-alanine, a new antimetabolite of phenylalanine and tyrosine inEscherichia coli

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Zusammenfassung

β-Pyrrolo-l-alanin, dessen Synthese beschrieben ist, hemmt das Wachstum vonE. coli B auf synthetischen Nährböden. Die Hemmung wird vonl-Phenylalanin undl-Tyrosin vollständig, vonl-Tryptophan teilweise, nicht aber von Histidin aufgehoben. Stämme vonE. coli, die gegenβ-Pyrrolo-l-alanin bzw.p-Fluorophenyl-dl-alanin resistent sind, zeigen gekreuzte Resistenz.

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Authors and Affiliations

  1. Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Science, Prague, Czechoslovakia

    K. Poduška, J. Glöde, V. Lisý, J. Škoda, H. Gross & J. Rudinger

  2. Institut für organische Chemie, Deutsche Akademie der Wissenschaften zu Berlin, Berlin-Adlershof, DDR

    K. Poduška, J. Glöde, V. Lisý, J. Škoda, H. Gross & J. Rudinger

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  1. K. Poduška
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  2. J. Glöde
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  3. V. Lisý
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  4. J. Škoda
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  5. H. Gross
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  6. J. Rudinger
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Poduška, K., Glöde, J., Lisý, V. et al. β-Pyrrolo-L-alanine, a new antimetabolite of phenylalanine and tyrosine inEscherichia coli. Experientia 22, 809–810 (1966). https://doi.org/10.1007/BF01897430

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  • DOI: https://doi.org/10.1007/BF01897430

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