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Sulfamidés et acides nucléiques

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Summary

The ribonucleic and thymonucleic acids are antisulphamide forEremothecium Ashbyii and for aSaccharomyces. This effect is due partly to purines, first of all to adenine, but not to any pyrimidines. ForSaccharomyces, the action of adenine is 1/10 of that of PAB acid. The suggestion is made that the bacteriostatic effect of the sulphamide is connected with the nucleic acids of the cytoplasma and the nucleus. Those are studied cytologically with help of the ribonuclease-method ofBrachet. Strong differences appear between the normal cells and the intoxicated ones.

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Literatur

  1. Ces faits ont été exposés le 27 janvier 1946 à l'assemblée de la Société suisse des Physiologistes et des Pharmacologues (Lausanne). VoirW. H. Schopfer etM. Guilloud, Helv. physiol. acta,4, C 24 (1946).

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Authors and Affiliations

  1. Institut botanique de l'Université de Berne, Switzerland

    W. H. Schopfer

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  1. W. H. Schopfer
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Schopfer, W.H. Sulfamidés et acides nucléiques. Experientia 2, 188–189 (1946). https://doi.org/10.1007/BF02156453

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  • DOI: https://doi.org/10.1007/BF02156453

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