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Effects of tybamate and pentylenetetrazol on spinal interneurons

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Zusammenfassung

Das Muskelrelaxans Tybamat ruft eine Hemmung der Aktivität spinaler Interneurone hervor, die von einer Blockade des spinalen polysynaptischen Reflexes begleitet ist. Pentylenetetrazol hingegen hebt die beiden durch Tybamat erzeugten Effekte auf, steigert zudem die interneuronale Aktivität, eine Eigenschaft, die die Verstärkung des polysynaptischen Reflexes erklären könnte.

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Authors and Affiliations

  1. Department of Pharmacology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, 10032, New York, N. Y., USA

    E. B. Kirsten & T. C. Tseng

Authors
  1. E. B. Kirsten
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  2. T. C. Tseng
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Kirsten, E.B., Tseng, T.C. Effects of tybamate and pentylenetetrazol on spinal interneurons. Experientia 28, 1459–1460 (1972). https://doi.org/10.1007/BF01957851

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