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Rapid Restitution of the Rat Pancreas following Acinar Cell Necrosis Subsequent to Ethionine

Nature volume 170, pages 929–930 (1952)Cite this article

Abstract

ONLY rarely has the suggestion been made that the pancreas, human1 or animal2, possesses the faculty of complete regeneration. Ethionine, a metabolic analogue of methionine, produces acinar cell necrosis of the pancreas3. Rats show within one to two weeks after pancreatic acinar cell necrosis a relatively complete restitution of the organ.

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References

  1. Parker, F., jun., J. Med. Res., 40, 471 (1919).

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  2. Bensely, R. R., “Harvey Lectures”, 1914–1915, 250 (J. B. Lippincott Co., Philadelphia, 1915).

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  3. Farber, E., and Popper, H., Proc. Soc. Exp. Biol. and Med., 74, 838 (1950). Goldberg, R. G., Chaikoff, I. L., Dodge, A. H., ibid., 74, 869 (1950).

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Authors and Affiliations

  1. Division of Pathology, Memorial Hospital,

    PATRICK J. FITZGERALD & MARIO ALVIZOURI

  2. Department of Physics, Sloan Kettering Institute, Memorial Hospital Center for Cancer and Allied Diseases, New York, N.Y.

    PATRICK J. FITZGERALD & MARIO ALVIZOURI

Authors
  1. PATRICK J. FITZGERALD
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  2. MARIO ALVIZOURI
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FITZGERALD, P., ALVIZOURI, M. Rapid Restitution of the Rat Pancreas following Acinar Cell Necrosis Subsequent to Ethionine. Nature 170, 929–930 (1952). https://doi.org/10.1038/170929b0

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  • DOI: https://doi.org/10.1038/170929b0

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