Abstract
BY the addition of protective agents, such as broth and gelatin, it has become possible to obtain X-ray survival curves for phages in solution which are the same as those obtained from dry phages1, thus making it possible to interpret the results as being due to direct hits of the radiation on the phages. This attractive possibility has been rendered tenuous by the finding of hyperprotection by irradiating at low temperatures2 or by irradiating in the presence of agents such as cysteine3. Both these devices decrease the slope of the survival curves by a factor of about 1.4. The purpose of this communication is to present a technique which decreases the slope of the survival curve by a factor of about 2.5.
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References
Adams, W. R., and Pollard, E., Arch. Biochem. Biophys., 36, 311 (1952).
Bachofer, C. S., Ehret, C. F., Mayer, S., and Powers, E. L., Proc. U.S. Nat. Acad. Sci., 39, 744 (1953).
Doermann, A. H. quoted in Watson, J. D., J. Bact., 63, 473 (1952).
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EPSTEIN, H., SCHARDL, D. Hyperprotection against Radiation by combining Addition of Cysteine with Lyophilization. Nature 179, 100 (1957). https://doi.org/10.1038/179100a0
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DOI: https://doi.org/10.1038/179100a0
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