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Adsorption and Hæmolytic Action of Diacetyldeoxycholate

Abstract

IN an investigation of the relation of the hæmolytic activity of sodium cetyl sulphate and sodium lauryl sulphate to their adsorption to red blood cells, we found that hæmolysis only starts when a minimum quantity of the detergent is really fixed to the cell walls1,2. On the assumption that such hæmolysis does not necessarily involve a unique mechanism, we undertook the study of the relationship between hæmolysis and adsorption for a bile acid derivative.

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References

  1. Ruyssen, R., and Croes, R., Med. Kon. Vlaam. Acad. Wetensch. Belg., 12, 4 (1950).

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  2. Croes, R., and Ruyssen, R., Bull. Soc. Chim. Biol., 33, 1837 (1951).

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  3. Ponder, E., “Hemolysis and Related Phenomena” (London, 1948).

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  4. Pethica, B. A., and Schulman, J. H., Nature, 170, 117 (1952).

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CROES, R., RUYSSEN, R. Adsorption and Hæmolytic Action of Diacetyldeoxycholate. Nature 171, 846–847 (1953). https://doi.org/10.1038/171846a0

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