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Mechanisms for memory types differ

Abstract

The formation of long-term memory takes several hours1,2,3, during which time memories rely on short-term systems1,2,4,5. For over 100 years1, the main unanswered question of memory research has been whether short-term memory is a necessary step towards long-term memory4,5, or whether they are separate processes1,2. Here we report four treatments that block short-term memory while leaving long-term memory intact, showing that these memory systems are separate to some degree.

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Figure 1: Data are expressed as median (interquartile range) test session latency in the step-down inhibitory avoidance task.

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Izquierdo, I., Barros, D., Mello e Souza, T. et al. Mechanisms for memory types differ. Nature 393, 635–636 (1998). https://doi.org/10.1038/31371

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