Highlights

Latest research

    1. Cell Biology
    2. Neuroscience

    Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

    Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
    Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
    1. Cancer Biology

    Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer

    Phaedra C. Ghazi, Kayla T. O’Toole ... Martin McMahon
    1. Cell Biology

    Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells

    Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
    1. Cancer Biology

    Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia

    Kyle Spinler, Michael Hamilton ... Tannishtha Reya
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine