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Abstract
▪ Abstract
Plant and fungal membrane proteins catalyzing the transmembrane translocation of small molecules without directly using ATP or acting as channels are discussed in this review. Facilitators, ion-cotransporters, and exchange translocators mainly for sugars, amino acids, and ions that have been cloned and characterized from Saccharomyces cerevisiae and from various plant sources have been tabulated. The membrane topology and structure of the most extensively studied carriers (lac permease of Escherichia coli, Glut1 of man, HUP1 of Chlorella) are discussed in detail as well as the kinetic analysis of specific Na+ and H+ cotransporters. Finally, the knowledge concerning regulatory phenomena of carriers—mainly of S. cerevisiae—is summarized.