Dietary management using immunostimulants to protect fish health and prevent bacterial infection is widely practiced. Many insect species possess various bioactive substances that can improve animal health. We previously identified several bioactive polysaccharides derived from insects, including dipterose-BSF from black soldier fly (Hermetia illucens) larvae; this can stimulate innate immunity in mammalian macrophage RAW264.7 cells. However, the effect of dietary dipterose-BSF on the immune system of teleosts remains unclear. Here, we analyzed the immune status of zebrafish (Danio rerio) after 14 days of dietary inclusion of dipterose-BSF (0.01, 0.1, and 1 µg/g), followed by an immersion challenge using Edwardsiella tarda. To identify changes in the transcriptional profile induced by dipterose-BSF, we performed RNA-sequencing analyses of the liver and intestine. Differentially expressed genes were investigated, with both organs showing several upregulated genes, dominated by nuclear factor and tumor necrosis factor family genes. Gene Ontology analysis revealed several terms were significantly higher in the experimental group compared with the control group. Challenge tests suggested that dietary dipterose-BSF had some positive effects on disease resistance in fish, but these effects were not pronounced. Full article

Considering the increasing need for sustainable and economical energy storage solutions, the integration of layered materials such as MoS₂ into these systems represents an important step toward enhancing energy sustainability and efficiency. Exploring environmentally responsible fabrication techniques, this study assesses wrinkled MoS₂ thin films synthesized from distinct Mo and MoS₂ targets, followed by sulfurization conducted in a graphite box. We utilized magnetron sputtering to deposit precursor Mo and MoS₂ films on Si substrates, achieving thicknesses below 20 nm. This novel approach decreases sulfur by up to tenfold during sulfurization due to the confined space technique, contributing also to avoiding the formation of toxic gases such as SO₂ or the necessity of using H₂S, aligning with sustainable materials development. Thinner MoS₂ layers were obtained post-sulfurization from the MoS₂ precursors, as shown by X-ray reflectometry. Raman spectroscopy and grazing X-ray diffraction analyses confirmed the amorphous nature of the as-deposited films. Post-sulfurization, both types of films exhibited crystalline hexagonal MoS₂ phases, with the sulfurized Mo showing a polycrystalline nature with a (100) orientation and sulfurized MoS₂ displaying a (00L) preferred orientation. The X-ray photoelectron spectroscopy results supported a Mo:S ratio of 1:2 on the surface of the films obtained using the MoS₂ precursor films, confirming the stoichiometry obtained by means of energy dispersive X-ray spectroscopy. Scanning electron microscopy and atomic force microscopy images revealed micrometer-sized clusters potentially formed during rapid cooling post-sulfurization, with an increased average roughness. These results open the way for the further exploration of wrinkled MoS₂ thin films in advanced energy storage technologies. Full article

The presence of enteric pathogens in produce can serve as a significant means of transmitting infections to consumers. Notably, tomatoes, as a type of produce, have been implicated in outbreaks caused by various human pathogens, such as Salmonella enterica and pathogenic Escherichia coli. However, the survival characteristics of Shigella spp. in tomatoes have not been thoroughly investigated. In this study, we assess the survival of S. flexneri 2a in two distinct varieties of post-harvested tomatoes. S. flexneri 2a was used to inoculate both regular-sized Vine tomatoes and cherry-type Mini Plum tomatoes. Our findings reveal no significant difference in Shigella survival in the pericarp of both varieties on day 2 post-inoculation. However, a significant disparity emerges on day 6, where all recovered Shigella colonies exclusively belong to the Mini Plum variety, with none associated with the Vine type. When Shigella was inoculated into the locular cavity (deep inoculation), no significant difference between varieties was observed. Additionally, we investigate the potential role of the SRL pathogenicity island (SRL PAI) in the survival and fitness of S. flexneri 2a in post-harvested tomatoes. Our results indicate that while the SRL PAI is not linked to the survival of the strains in tomato, it does impact their fitness. These findings underscore the variability in Shigella strains’ survival capabilities depending on the tomato variety, highlighting the importance of understanding Shigella ecology beyond the human host and identifying molecular determinants influencing bacterial survival to mitigate the risk of future outbreaks. The significance of this data on Shigella persistence in fresh vegetables should not be underestimated, as even a small number of Shigella cells can pose a threat to the health of individuals. Full article

This study aimed to develop a remote sensing method for estimating the aboveground fresh weight (AGFW) of sugarcane using multispectral images and light detection and ranging (LiDAR). Remotely sensed data were acquired from an unmanned aerial vehicle (drone). Sample plots were harvested and the AGFW of each plot was measured. Sugarcane crown heights and volumes were obtained by isolating individual tree crowns using a LiDAR-derived digital surface model of the area. Multiple linear regression (MLR) and partial least-squares regression (PLSR) models were tested for the field-sampled AGFWs (dependent variable) and individual canopy heights and volumes, and spectral indices were used as independent variables or predictors. The PLSR model showed more promising results than the MLR model when predicting the AGFW over the study area. Although PLSR is well-suited to a large number of collinear predictor variables and a limited number of field samples, this study showed moderate results (R² = 0.5). The visual appearance of the spatial distribution of the AGFW map is satisfactory. The limited no. of field samples overfitted the MLR prediction results. Overall, this research highlights the potential of integrating remote sensing technologies in the sugarcane industry, thereby improving yield estimation and effective crop management. Full article

Institutional, policy, and management scholars and practitioners are increasingly interested in leveraging network perspectives, methods, and data to understand complex social phenomena, including the various stages of the policy process, community mobilization, and coupled natural and human systems. Viewing these phenomena through the lens of system-oriented networks can be valuable for understanding and intervening within complex policy arenas. However, currently, there is no clear consensus on who and what constitutes a relevant actor in a system-oriented network. Furthermore, numerous conceptual and methodological traditions for conceptualizing, measuring, and analyzing system-oriented networks have arisen, and each is linked to different disciplinary traditions. In this paper, we showcase six approaches from the public policy and public management literature for conceptualizing and analyzing system-oriented networks. We offer a conceptual framework for characterizing different approaches which considers differences in their focal system of interest, analytical focus, theoretical orientation, and approach for determining network boundaries. We review these elements with an eye toward helping scholars and practitioners interested in system-oriented networks to make informed decisions about the array of available approaches. Full article

The authors present a practical framework for assessing seasonal events that may influence maritime operations, seeking to tie in discussions about climate change adoption to maritime operational assessments. Most maritime-related research tends to focus on a single event, such as a storm, but maritime systems operate within complex systems that have some predictable patterns. These predictable patterns due to natural events, such as weather and water levels, can influence operations. By contrast, other factors, such as cargo peaks or cultural activities, could also shape maritime systems. The growing focus on adopting human activities to the United Nations’ Sustainability Development Goals means that system operations should consider their relationship to these broader goals. By integrating data from emergency management databases and weather information sources with other inputs, the authors, in collaboration with various stakeholder groups, created a matrix of regionally specific predictable events that may occur within a region by time of year that can be linked to the Sustainability Development Goals. The matrix was vetted to verify the information, ensuring that all perspectives were considered. The main findings were that a seasonal event matrix was not just a theoretical tool but a practical reference for examining operational patterns in a river for various uses, such as training, operational planning, and emergency response coordination. Full article

Background: The occurrence of ventricular tachyarrhythmias represents an established risk factor of mortality in heart failure (HF). However, data concerning their prognostic impact in heart failure with mildly reduced ejection fraction (HFmrEF) is limited. Therefore, the present study aims to investigate patient characteristics associated with ventricular tachyarrhythmias and their prognostic impact in patients with HFmrEF. Methods: Consecutive patients hospitalized with HFmrEF (i.e., left ventricular ejection fraction 41–49% and signs and/or symptoms of HF) were retrospectively included at one institution from 2016 to 2022. The prognosis of patients with HFmrEF and different types of ventricular tachyarrhythmias (i.e., non-sustained ventricular tachycardia (nsVT), sustained VT (sVT), and ventricular fibrillation (VF) was investigated for the primary endpoint of long-term all-cause mortality at 30 months. Secondary endpoints included in-hospital all-cause mortality and long-term HF-related rehospitalization at 30 months. Results: From a total of 2184 patients with HFmrEF, 4.4% experienced ventricular tachyarrhythmias (i.e., 2.0% nsVT, 0.7% sVT, and 1.6% VF). The occurrence of nsVT was associated with higher New York Heart Association (NYHA) functional class, whereas the incidence of sVT/VF was associated with acute myocardial infarction and ischemic heart disease. However, nsVT (25.0%; HR = 0.760; 95% CI 0.419–1.380; p = 0.367) and sVT/VF (28.8%; HR = 0.928; 95% CI 0.556–1.549; p = 0.776) were not associated with a higher risk of long-term all-cause mortality compared to patients with HFmrEF without ventricular tachyarrhythmias (31.5%). In-hospital cardiovascular mortality was more frequently observed in patients with HFmrEF and sVT/VF compared to those with HFmrEF but without sustained ventricular tachyarrhythmias (7.7% vs. 1.5%; p = 0.004). Finally, the risk of rehospitalization for worsening HF was not affected by the presence of ventricular tachyarrhythmias. Conclusions: The occurrence of ventricular tachyarrhythmias in patients hospitalized with HFmrEF was low and not associated with long-term prognosis. Full article

The Rudny Altai is a western segment of the Altai orogenic belt. Its geological richness makes its geoheritage exploration an urgent matter. Investigations in the Loktevsky District (Altai Region, Russian Federation) have led to the finding of three notable localities, which are proposed as geosites. Field investigations and both qualitative and semi-quantitative (scoring by criteria) studies were carried out to characterize and value the geoheritage properties of these localities. The Neverovsky palaeoreef is a relatively large geosite, representing a Frasnian reef developed on a volcanic edifice. The Zolotukha section and the Razdolnoe section are smaller geosites representing deep-marine facies of the Giventian–Frasnian transition and the late Frasnian, respectively. Seven geoheritage types are established in the Neverovsky palaeoreef, and four geoheritage types are established in the other two geosites. Examination of rarity, accessibility, vulnerability, and other properties allows the ranking of the Neverovsky palaeoreef globally and the other two geosites regionally. The three proposed geosites need special geoconservation measures (especially regarding their rich fossil content). The palaeoreef can be used for the promotion of local tourism. Full article

User-generated passwords often pose a security risk in authentication systems. However, providing a comparative substitute poses a challenge, given the common tradeoff between security and user experience. This paper integrates cryptographic methods (both asymmetric and symmetric), steganography, and a combination of physiological and behavioural biometrics to construct a prototype for a passwordless authentication system. We demonstrate the feasibility of scalable passwordless authentication while maintaining a balance between usability and security. We employ threat modeling techniques to pinpoint the security prerequisites for the system, along with choosing appropriate cryptographic protocols. In addition, a comparative analysis is conducted, examining the security impacts of the proposed system in contrast to that of traditional password-based systems. The results from the prototype indicate that authentication is possible within a timeframe similar to passwords (within 2 s), without imposing additional hardware costs on users to enhance security or compromising usability. Given the scalable nature of the system design and the elimination of shared secrets, the financial and efficiency burdens associated with password resets are alleviated. Furthermore, the risk of breaches is mitigated as there is no longer a need to store passwords and/or their hashes. Differing from prior research, our study presents a pragmatic design and prototype that deserves consideration as a viable alternative for both password-based and passwordless authentication systems. Full article

This paper proposes a quadrotor system control scheme using an intelligent–proportional–integral–differential control (I-PID)-based controller augmented with a radial basis neural network (RBF neural network) and the proposed adaptive robust term. The I-PID controller, similar to the widely utilized PID controller in quadrotor systems, demonstrates notable robustness. To enhance this robustness further, the time-delay estimation error was compensated with an RBF neural network. Additionally, an adaptive robust term was proposed to address the shortcomings of the neural network system, thereby constructing a more robust controller. This supplementary control input integrated an adaptation term to address significant signal changes and was amalgamated with a reverse saturation filter to remove unnecessary control input during a steady state. The adaptive law of the proposed controller was designed based on Lyapunov stability to satisfy control system stability. To verify the control system, simulations were conducted on a quadrotor system maneuvering along a spiral path in a disturbed environment. The simulation results demonstrate that the proposed controller achieves high tracking performance across all six axes. Therefore, the controller proposed in this paper can be configured similarly to the previous PID controller and shows satisfactory performance. Full article

Companies are increasingly focusing on sustainable business practices. Internal and external stakeholders’ expectations manifest in legal requirements, national and international standards, and market and customer expectations, among other things, must be considered. In addition to profit maximization, which is the usual target for corporate management, management must consider environmental sustainability aspects such as resource efficiency, greenhouse gas intensity, and a company’s emissions behavior. In addition, social aspects related to the company’s employees, the immediate urban environment, the situation in the supply chain, and effects on the market environment must increasingly be considered. Specifically, companies are faced with the challenge of dealing with conflicting objectives regarding the various aspects of sustainability and, if necessary, weighing them up against each other. These trade-offs must be made against the company’s socio-economic and ecological environment, corporate strategy, and sustainability goals. This paper provides an overview of current approaches and research gaps on this topic through a literature review. It highlights the lack of methods and frameworks to specifically deal with trade-offs and conflicts between goals. Full article

Efficiency in stock markets is essential for economic stability and growth. This study investigates the efficiency and herding behavior of the stock markets from the top economies of the world (known as G20 countries). We classify stock market indices using MSCI classification for the developed and emerging markets to provide a comparative examination using the latest data and by employing the robust multifractal detrended fluctuation (MFDFA) method. In addition to the full sample, the analysis uses sub-sample periods to reveal the hidden features and efficiencies of the G20 markets during the Russia–Ukraine War and COVID-19 for the first time. The findings show the availability of varied multifractality among all G20 stock markets during the overall and crisis periods, exhibit long-range correlations, and may support the fractal market hypothesis. In addition, Italy remains the least efficient, while Germany remains the most efficient stock market. The sub-sample results further reveal unevenness in the local fluctuations and resultant higher inefficiency considering the sheer magnitude and impact of crises on the G20 stock markets. However, the efficiency of developed stock markets performed better as compared to emerging markets. The study of G20 stock markets is useful and provides several implications for a wider audience. Full article

Plastics offer many advantages and are widely used in various fields. Nevertheless, most plastics derived from petroleum are slow to degrade due to their stable polymer structure, posing serious threats to organisms and ecosystems. Thus, developing environmentally friendly and biodegradable plastics is imperative. In this study, biodegradable cellulose/multi-walled carbon nanotube (MCNT) hybrid gels and films with improved ultraviolet-shielding properties were successfully prepared using cotton textile waste as a resource. It was proven that MCNTs can be dispersed evenly in cellulose without any chemical or physical pretreatment. It was found that the contents of MCNTs had obvious effects on the structures and properties of hybrid films. Particularly, the averaged transmittance of cellulose/MCNT composite films in the range of 320–400 nm (T_320–400) and 290–320 nm (T_290–320) can be as low as 19.91% and 16.09%, when the content of MCNTs was 4.0%, much lower than those of pure cellulose films (T_320–400: 84.12% and T_290–320: 80.03%). Meanwhile, the water contact angles of the cellulose/MCNT films were increased by increasing the content of MCNTs. Most importantly, the mechanical performance of cellulose/MCNT films could be controlled by the additives of glycerol and MCNTs. The tensile strength of the cellulose/MCNT films was able to reach as high as 20.58 MPa, while the elongation at break was about 31.35%. To summarize, transparent cellulose/MCNT composites with enhanced ultraviolet-shielding properties can be manufactured successfully from low-cost cotton textile waste, which is beneficial not only in terms of environmental protection, but also the utilization of natural resources. Full article

Background: Physical activity contributes to both physiological and psychosocial benefits for children and adolescents with disabilities. However, the prevalence of physical inactivity is notably higher among disabled young people compared to their healthy peers. Despite this, there is a lack of constructed knowledge structure, evolutionary path, research hotspots, and frontiers in studies related to physical activity in young people with disabilities.Methods: The literature related to the research of physical activity in children and adolescents with disabilities was retrieved from the core collection of the Web of Science. The annual publication numbers and the timing, frequency, and centrality of the co-occurrence network with respect to journals, countries, institutions, authors, references, and keywords were analyzed. Additionally, clustering analysis and burst analysis were performed on the references and keywords. All analyses were conducted using CiteSpace. Results: A total of 1308 related articles were included. The knowledge structure of research on the physical activity of disabled children and adolescents, including annual publication numbers, influencing journals, countries, institutions, authors, references, and keywords along with their respective collaborative networks, has been constructed. Furthermore, the research foundation, current hot topics, and research frontiers have been identified by analyzing references and keywords. Conclusions: Current research hotspots include interventions, therapies, and programs aimed at enhancing specific skills, as well as addressing the satisfaction of competence to improve motivation and the effectiveness of physical activity. There is also a focus on the development of scales for quantitative studies. Future directions may be toward personalized interventions or programs to enhance physical activity levels among youth with disabilities. Full article

Systemic inflammation and coronary microvascular endothelial dysfunction are essential pathophysiological factors in heart failure (HF) with preserved ejection fraction (HFpEF) that support the use of statins. The pleiotropic properties of statins, such as anti-inflammatory, antihypertrophic, antifibrotic, and antioxidant effects, are generally accepted and may be beneficial in HF, especially in HFpEF. Numerous observational clinical trials have consistently shown a beneficial prognostic effect of statins in patients with HFpEF, while the results of two larger trials in patients with HFrEF have been controversial. Such differences may be related to a more pronounced impact of the pleiotropic properties of statins on the pathophysiology of HFpEF and pro-inflammatory comorbidities (arterial hypertension, diabetes mellitus, obesity, chronic kidney disease) that are more common in HFpEF. This review discusses the potential mechanisms of statin action that may be beneficial for patients with HFpEF, as well as clinical trials that have evaluated the statin effects on left ventricular diastolic function and clinical outcomes in patients with HFpEF. Full article

This brief narrative review assesses how digital technologies—such as wearables, mobile health apps, and various digital tools such as computers, game consoles, tablets, smartphones, and extended reality systems—can influence sedentary and physical activity behaviors among community-dwelling older adults. Each section highlights the central role of these technologies in promoting active aging through increased motivation, engagement and customized experiences. It underlines the critical importance of functionality, usability and adaptability of devices and confirms the effectiveness of digital interventions in increasing physical activity and reducing sedentary behavior. The sustainable impact of these technologies needs to be further investigated, with a focus on adapting digital health strategies to the specific needs of older people. The research advocates an interdisciplinary approach and points out that such collaborations are essential for the development of accessible, effective and ethical solutions. This perspective emphasizes the potential of digital tools to improve the health and well-being of the aging population and recommends their strategic integration into health promotion and policy making. Full article

In the context of increasing reliance on mobile devices, robust personal security solutions are critical. This paper presents Zero-FVeinNet, an innovative, lightweight convolutional neural network (CNN) tailored for finger vein recognition on mobile and embedded devices, which are typically resource-constrained. The model integrates cutting-edge features such as Zero-Shuffle Coordinate Attention and a blur pool layer, enhancing architectural efficiency and recognition accuracy under various imaging conditions. A notable reduction in computational demands is achieved through an optimized design involving only 0.3 M parameters, thereby enabling faster processing and reduced energy consumption, which is essential for mobile applications. An empirical evaluation on several leading public finger vein datasets demonstrates that Zero-FVeinNet not only outperforms traditional biometric systems in speed and efficiency but also establishes new standards in biometric identity verification. The Zero-FVeinNet achieves a Correct Identification Rate (CIR) of 99.9% on the FV-USM dataset, with a similarly high accuracy on other datasets. This paper underscores the potential of Zero-FVeinNet to significantly enhance security features on mobile devices by merging high accuracy with operational efficiency, paving the way for advanced biometric verification technologies. Full article

Clearing and successfully characterizing ecosystem service flow paths has become a key bottleneck restricting in-depth research on the supply and demand relationships of ecosystem services. At present, although some explorations have been performed using water ecosystem services as a pioneer, the nature of its network and the fact that ecological base flow needs to be eliminated have been ignored. This study used InVEST and network models to consider ecological base flow, quantifying the supply, demand, and flow paths of freshwater ecosystem services in the Xiangjiang River Basin. The results showed that the overall distribution of the water supply in the Xiangjiang River Basin from 2000 to 2020 shows a pattern of higher supply in the south and lower supply in the north. The distribution of water demand shows higher levels in the north and lower levels in the south. The network density remains at its maximum level. The results of this study have provided a scientific basis for water resource management in river basins and improving ecological compensation mechanisms. Full article

Hemp (Cannabis sativa L.) has experienced a significant resurgence in popularity, and global interest in diversifying its use in various industries, including the food industry, is growing. Therefore, due to their exceptional nutritional value, hemp seeds have recently gained increasing interest as a valuable ingredient for obtaining high-quality foods and dietary supplements. Hemp seeds stand out for their remarkable content of quality proteins, including edestin and albumin, two distinct types of proteins that contribute to exceptional nutritional value. Hemp seeds are also rich in healthy lipids with a high content of polyunsaturated fatty acids, such as linoleic acid (omega-6), alpha-linolenic acid (omega-3), and some vitamins (vitamins E, D, and A). Polyphenols and terpenoids, in particular, present in hemp seeds, provide antimicrobial, antioxidant, and anti-inflammatory properties. This review examines the scientific literature regarding hemp seeds’ physicochemical and nutritional characteristics. The focus is on those characteristics that allow for their use in the food industry, aiming to transform ordinary food products into functional foods, offering additional benefits for the body’s health. Innovating opportunities to develop healthy, nutritionally superior food products are explored by integrating hemp seeds into food processes, promoting a balanced and sustainable diet. Full article

Safety is essential for sustainable aviation fuels (SAFs). However, evaluating SAFs’ impacts on aero-engine safety is challenging because it involves multiple space scales and the strongly coupled relationships of aero-engine components. Aiming at addressing this problem, a model-based approach is proposed to establish the relationship between the fuel-level physical properties and engine-level safety parameters. Firstly, a unified modeling criterion is proposed to consider the interrelations of aero-engine components. Under this criterion, aero-engine secondary air system (SAS) components are included in SAF safety assessment, since they have non-neglectable influences on aero-engine safety. Secondly, this paper proposes a surrogate-based iteration strategy to embed the combustor’s high-dimensional computational fluid dynamics (CFD) model into the aero-engine flow network model. Then, the proposed model-based safety assessment approach is applied to a Fischer–Tropsch hydro-processed synthesized paraffinic kerosine (F-T SPK) safety assessment case. The effects of fuel flow and blending ratio are considered. The results indicate the necessity to evaluate SAFs’ safety at the aero-engine level and consider the influences of SAS components. The proposed model-based approach may provide a preliminary screening before SAFs’ certification tests. This convenience may be beneficial for reducing the cost and accelerating SAFs’ application. Full article

Ensuring security in electronic examination systems represents a significant challenge, particularly when practical considerations dictate that most involved parties cannot be fully trusted due to self-interest. To enhance the security, we introduce auditability to e-exam systems, enabling an auditing authority to verify the system integrity. This auditability not only ensures system robustness but also creates an opportunity to grant communication between candidates and examiners, allowing for clarification on unclear questions during exams. Additionally, the implementation of attribute-based certifications ensures anonymity for both candidates and examiners throughout all stages of the exam, with the option for revocation in case of audit-detected fraud. Full article

Electrospark coatings alloyed with MoS₂ have been studied. The coatings were obtained by the following two strategies: the first consisted of pre-applying molybdenum disulfide to the treated surface and alloying with a molybdenum electrode (Mo + MoS₂ coating); the second consisted of applying a paste with a sulfur content of 33.3% to the treated surface and alloying with a molybdenum electrode (Mo + S coating). The structure, phase composition, and tribological properties of the coatings were investigated. The coatings have a complex structure consisting of an upper soft layer, a hardened white layer, a diffusion zone, and a substrate. Element analysis and cross-sectional hardness changes indicated that element diffusion occurred at the coating/substrate interface. The phase composition of the coatings is represented by BCC and FCC solid solutions on Fe, and MoS₂ is also detected. In Mo + S coatings, the molybdenum disulfide on the surface is about 8%; in Mo + MoS₂ coatings, it is 27%–46%. The obtained coatings show very good tribological properties compared to molybdenum ESA coatings. The frictional forces and coefficients are reduced by a factor of 10 and 40, depending on the test conditions. Full article