ExLibris header image
SFX Logo
Title: Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor
Source:

Proceedings of the National Academy of Sciences of the United States of America [0027-8424] Biggadike, K yr:2009


Collapse list of basic services Basic
Full text
Full text available via PubMed Central
GO
Document delivery
Request document via Library/Bibliothek GO
Users interested in this article also expressed an interest in the following:
1. Biggadike, K. "X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain." Journal of medicinal chemistry 51.12 (2008): 3349-3352. Link to Full Text for this item Link to SFX for this item
2. Wang, H. "Induced-fit docking of mometasone furoate and further evidence for glucocorticoid receptor 17 alpha pocket flexibility." Journal of molecular graphics and modelling 27.4 (2008): 512-521. Link to SFX for this item
3. Madauss, K. "The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist." Bioorganic & medicinal chemistry letters 18.23 (2008): 6097-6099. Link to SFX for this item
4. Charles, V. "Update on the current use of hormonals as therapy in advanced breast cancer." Anti-cancer drugs 14.4 (2003): 265-73. Link to SFX for this item
5. Islam, K. "Directed evolution of estrogen receptor proteins with altered ligand-binding specificities." Protein engineering, design & selection 22.1 (2008): 45-52. Link to SFX for this item
6. Proksch, E. "The Role of Emollients in the Management of Diseases with Chronic Dry Skin." Skin pharmacology and physiology 21.2 (2007): 75-80. Link to SFX for this item
7. Biggadike, Keith B. "X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain⊥." Journal of medicinal chemistry 51.12 (2008): 3349-3352. Link to Full Text for this item Link to SFX for this item
8. Hui, Mirta L. "Association between exposure to topical tacrolimus or pimecrolimus and cancers." The Annals of pharmacotherapy 43.12 (2009): 1956-1963. Link to SFX for this item
9. Lodén, M. "Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders." American journal of clinical dermatology 4.11 (2003): 771-88. Link to SFX for this item
10. Svensson, C K K. "Cutaneous drug reactions." Pharmacological reviews 53.3 (2001): 357-79. Link to SFX for this item
11. Proksch, E. "The management of dry skin with topical emollients--recent perspectives." Journal der Deutschen Dermatologischen Gesellschaft 3.10 (2005): 768-774. Link to Full Text for this item Link to SFX for this item
12. Hogger, P. "Binding kinetics of fluticasone propionate to the human glucocorticoid receptor." Steroids 59.10 (1994): 597-602. Link to Full Text for this item Link to SFX for this item
13. Eichenfield, Lawrence F. "Guidelines of care for the management of atopic dermatitis." Journal of the American Academy of Dermatology 70.2 (2013): 338-351. Link to SFX for this item
14. Pessin, M E. "Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling." The Journal of biological chemistry 276.45 (2001): 42436-44. Link to SFX for this item
15. He, Y. "Structures and mechanism for the design of highly potent glucocorticoids." Cell Research 24.6 (2014): 713-726. Link to Full Text for this item Link to SFX for this item
16. Kohn, Jeffrey A. "Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors." Journal of biological chemistry 287.20 (2012): 16267-16275. Link to Full Text for this item Link to SFX for this item
17. Amat, R. "RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells." Journal of cellular physiology 226.2 (2010): 293-8. Link to Full Text for this item Link to SFX for this item
18. Giovanni, B. "Are some progestins genotoxic liver carcinogens?" Mutation research 512.2-3 (2002): 155-163. Link to SFX for this item
19. EMANUELE, J. "MECHANISTIC STUDIES OF THE FLAVOPROTEIN TRYPTOPHAN 2-MONOOXYGENASE .2. PH AND KINETIC ISOTOPE EFFECTS." Biochemistry 34.11 (1995): 3716-3723. Link to Full Text for this item Link to SFX for this item
20. Kone, F. "Digital screening methodology for the directed evolution of transglycosidases." Protein engineering, design & selection 22.1 (2009): 37-44. Link to SFX for this item
View More...
View Less...
Select All Clear All

Expand list of advanced services Advanced