ExLibris header image
SFX Logo
Title: A Practical Synthesis of the PDE4 Inhibitor, SB-207499, from a Cyclohexanone Precursor
Source:

Organic Process Research & development [1083-6160] Badham, Neil yr:2002


Collapse list of basic services Basic
Full text
Full text available via American Chemical Society Journals
GO
Document delivery
Request document via Library/Bibliothek GO
Users interested in this article also expressed an interest in the following:
1. Staderini, M. "Lewis Acid-Catalyzed Generation of CC and CN Bonds on π-Deficient Heterocyclic Substrates." Advanced synthesis & catalysis 357.1 (2014): 185-195. Link to Full Text for this item Link to SFX for this item
2. Hung, Su H. "A nonhydrolyzable reactive cAMP analogue, (S-p)-8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3 ',5 '-cyclic S-(methyl)monophosphorothioate, irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase at micromolar concentrations." Biochemistry 41.9 (2002): 2962-2969. Link to Full Text for this item Link to SFX for this item
3. Kim, H. "High-performance liquid chromatographic analysis of the D4 receptor antagonist SCH 66712 in rat plasma." Journal of chromatography. B, Biomedical applications 735.1 (1999): 11-47. Link to Full Text for this item Link to SFX for this item
4. Badham, Neil F. "Homologation of ketones into carboxylic acids." Tetrahedron 60.1 (2004): 11-42. Link to SFX for this item
5. Wang, T. "Synthesis of improved lysomotropic autophagy inhibitors." Journal of medicinal chemistry 58.7 (2015): 3025-3035. Link to Full Text for this item Link to SFX for this item
6. Koley, S. "Lewis acid mediated three-component one-flask regioselective synthesis of densely functionalized 4-amino-1,2-dihydropyridines via cascade Knoevenagel/Michael/cyclization sequence." Tetrahedron 71.2 (2015): 301-307. Link to SFX for this item
7. Nomiyama, S. "Metal-Free Regioselective β-Alkylation of Pyrroles with Carbonyl Compounds and Hydrosilanes: Use of a Brønsted Acid as a Catalyst." Advanced synthesis & catalysis 356.18 (2014): 3881-3891. Link to Full Text for this item Link to SFX for this item
8. Gómez Barrio, A. "In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents." Bioorganic and medicinal chemistry letters 24.4 (2014): 1209-1213. Link to SFX for this item
9. Kelly, JJ. "Characterization of phosphodiesterase 4 in guinea-pig macrophages: Multiple activities, association states and sensitivity to selective inhibitors." British journal of pharmacology 124.1 (1998): 129-140. Link to Full Text for this item Link to SFX for this item
10. Hedenstrom, E. "Do enzymes recognise remotely located stereocentres? Highly enantioselective Candida rugosa lipase-catalysed esterification of the 2- to 8-methyldecanoic acids." Tetrahedron, asymmetry 13.8 (2002): 835-844. Link to Full Text for this item Link to SFX for this item
11. CHAN, TH D. "CONVERSION OF PRIMARY AMIDES INTO ACTIVE ACYLATING AGENTS VIA ACYLPYRROLES." Tetrahedron letters; 24.15 (1983): 1569-1572. Link to Full Text for this item Link to SFX for this item
12. Kloubert, S. "A direct and efficient synthetic method for nitriles from ketones." Synthetic communications 30.16 (2000): 2873-2887. Link to Full Text for this item Link to SFX for this item
13. Adlington, Robert M. "Recent applications of the Shapiro reaction." Accounts of chemical research 16.2 (1983): 55-59. Link to Full Text for this item Link to SFX for this item
14. Zhang, T. "Simultaneous analysis of basic, acidic and neutral compounds on an endcapped octadecylsilane silica-based monolith by pressure-assisted capillary electrochromatography." Electrophoresis 29.4 (2008): 944-951. Link to Full Text for this item Link to SFX for this item
15. Mintun, Mark A. "A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography." Annals of neurology 15.3 (1984): 217-227. Link to Full Text for this item Link to SFX for this item
16. Shoji, M. "Total synthesis of (+)-epoxyquinols A and B." Angewandte Chemie (International ed.) 41.17 (2002): 3192-3194. Link to Full Text for this item Link to SFX for this item
17. Diaz-Cruz, Damia S. "Determination of antimicrobial residues and metabolites in the aquatic environment by liquid chromatography tandem mass spectrometry." Analytical and bioanalytical chemistry 386.4 (2006): 973-985. Link to Full Text for this item Link to SFX for this item
18. Grossman, M J J. "Leptomeningeal carcinomatosis." Cancer Treatment Reviews 25.2 (1999): 103-19. Link to Full Text for this item Link to SFX for this item
19. HOFER, Jeffrey D. "Is HPLC assay for drug substance a useful quality control attribute?" Journal of Pharmaceutical and Biomedical Analysis 44.4 (2007): 906-913. Link to SFX for this item
20. Chen, JQ Q. "Recent advancements in ethylene and propylene production using the UOP/Hydro MTO process." Catalysis today 106.1-4 (2005): 103-107. Link to SFX for this item
View More...
View Less...
Select All Clear All

Expand list of advanced services Advanced