SFX by Ex Libris Inc.

Title:	Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle
Source:	Journal of Medicinal Chemistry [0022-2623] Le Manach, Claire yr:2016

Basic

Full text

Full text available via American Chemical Society Journals

Year:

Volume:

Issue:

Start Page:

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	CHHABRIA, Mahesh T. "Synthesis and biological evaluation of some 5-ethoxycarbonyl-6-isopropylamino-4-(substituted phenyl)aminopyrimidines as potent analgesic and anti-inflammatory agents." Bioorganic & medicinal chemistry letters 17.4 (2007): 1022-3332.
description	2.	"]indoles as Selective Toll-Like Receptor 4 Ligands." Journal of medicinal chemistry. 56.11: 4206-4223.
description	3.	Shivaprakash, S. "Synthesis and in-vitro study of novel (Z)-1-benzhydryl-4-cinnamylpiperazine derivatives as potential anticancer agents." International journal of pharmacy and pharmaceutical sciences 7.1 (2015): 416-420.
description	4.	Aneja, Chetan R. "Syntheses, biological evaluation and photophysical studies of novel 1,2,3-triazole linked azo dyes." RSC Advances 4.12 (2014): 5915-5926.
description	5.	Schmitt, L. "ATP-Lipids-Protein Anchor and Energy Source in Two Dimensions." Journal of the American Chemical Society 118.24 (1996): 5532-5543.
description	6.	Brimble, Margaret A. "Synthesis of naphthyl C-glycosides of rearranged tri-O-benzyl-2-deoxy-D-glucose." Tetrahedron letters 41.7 (2000): 1107-1110.
description	7.	Kriechbaum, M. "Peptide coupling between amino acids and the carboxylic acid of a functionalized chlorido-gold(I)-phosphane." Inorganic chemistry 53.19 (2014): 10602-10610.
description	8.	Forns, P. "Pyrazine-based Syk kinase inhibitors." Bioorganic and medicinal chemistry letters 22.8 (2012): 2784-2788.
description	9.	Plisson, C. "Evaluation of Carbon-11-Labeled 2Î²-Carbomethoxy-3Î²-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a Potential Radioligand for Imaging the Serotonin Transporter by PET." Journal of medicinal chemistry 49.3 (2006): 942-946.
description	10.	Kappler, F. "Approaches to isozyme-specific inhibitors. 17. Attachment of a selectivity-inducing substituent to a multisubstrate adduct. Implications for facilitated design of potent, isozyme-selective inhibitors." Journal of medicinal chemistry 33.9 (1990): 2545-.
description	11.	Li, J. "Ethers as hydrogen sources in BF3Â·OEt2promoted reduction of diphenylmethyl alcohols, ethers and esters to hydrocarbons." RSC Advances 5.104 (2015): 85291-85295.
description	12.	Srivastava, K. "Vibrational analysis and chemical activity of paracetamol–oxalic acid cocrystal based on monomer and dimer calculations: DFT and AIM approach." RSC Advances 6.12 (2016): 10024-10037.
description	13.	Xu, G. "Synthesis of maleimide derivatives via CuAAC click chemistry and biological evaluation of their antitumor activity against cancer cell lines." Journal of Chemical and Pharmaceutical Research 6.5 (2014): 947-951.
description	14.	Santhoshi, A. "Synthesis of 1-benzhydryl piperazine derivatives and evaluation of their ACE inhibition and antimicrobial activities." Medicinal chemistry research 23.6 (2014): 1-13.
description	15.	Wang, Xin u. "Gold-Catalyzed Oxidative Rearrangement Involving 1,2-Acyl Migration: Efficient Synthesis of Functionalized Dihydro-γ-Carbolines from α-(2-Indolyl) Propargylic Alcohols and Imines." Angewandte Chemie (International ed.) 52.50 (2013): 13302-13306.
description	16.	Mojtahedi, M. "Efficient and Rapid Solvent-Free Acetylation of Alcohols, Phenols, and Thiols Using Catalytic Amounts of Sodium Acetate Trihydrate." Journal of Chemistry 2013 (2013): 1-7.
description	17.	Berg, R. "Highly Active Dinuclear Copper Catalysts for Homogeneous Azide-Alkyne Cycloadditions." Advanced synthesis & catalysis 354.18 (2012): 3445-3450.
description	18.	Ramirez. "PHOSPHORYL TRANSFER FROM PHENYL AND 4-NITROPHENYL PHOSPHATES IN APROTIC AND PROTIC SOLVENTS. AMINE CATALYSIS AND FORMATION OF OXYPHOSPHORANE AND METAPHOSPHATE INTERMEDIATES." Tetrahedron 36 (1980): 3151-.
description	19.	Wang, P. "Single-Chain Nanoparticles with Well-Defined Structure via Intramolecular Crosslinking of Linear Polymers with Pendant Benzoxazine Groups." Journal of polymer science. Part A, Polymer chemistry 49.24 (2011): 5133-5141.
description	20.	Sawant, R. "Intra- and Intermolecular Oxa-Pictet-Spengler Cyclization Strategy for the Enantioselective Synthesis of Deoxy Analogues of (+)-Nanomycin A Methyl Ester, (+)-Eleutherin, (+)-Allo-Eleutherin, and (+)-Thysanone." European journal of organic chemistry 23 (2010): 4442-4449.