SFX by Ex Libris Inc.

Title:	Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity
Source:	Journal of Medicinal Chemistry [0022-2623] Davoren, Jennifer yr:2017

Basic

Full text

Full text available via American Chemical Society Journals

Year:

Volume:

Issue:

Start Page:

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Campbell, Elizabeth A. "Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase." Cell 104.6 (2001): 901-912.
description	2.	Seebach, D. "The world of beta- and gamma-peptides comprised of homologated proteinogenic amino acids and other components." Chemistry & biodiversity 1.8 (2004): 1111-1239.
description	3.	Gudkov, Andrei V V. "Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation." Nature chemical biology 2.9 (2006): 474-9.
description	4.	Yang, Y. "Synthesis of some 5-substituted indoles." Heterocycles 34.6 (1992): 1169-1175.
description	5.	MASUDA, N. "Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives." Bioorganic & medicinal chemistry 13.4 (2005): 949-61.
description	6.	Miller, Jeffrey H. "Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome." DNA repair 2.5 (2003): 593-608.
description	7.	Sharma, D. "Mutational Analysis of S12 Protein and Implications for the Accuracy of Decoding by the Ribosome." Journal of molecular biology 374.4 (2007): 1065-1076.
description	8.	Artsimovitch, Irina, I. "Allosteric Modulation of the RNA Polymerase Catalytic Reaction Is an Essential Component of Transcription Control by Rifamycins." Cell 122.3 (2005): 351-363.
description	9.	Floss, Heinz G. "Rifamycin-Mode of Action, Resistance, and Biosynthesis." Chemical reviews 105.2 (2005): 621-32.
description	10.	Xaplanteri, M. "Effect of polyamines on the inhibition of peptidyltransferase by antibiotics: revisiting the mechanism of chloramphenicol action." Nucleic Acids Research 31.17 (2003): 5074-5083.
description	11.	Qiao, Y. "Photoinduced Miyaura Borylation by a Rare-Earth-Metal Photoreductant: The Hexachlorocerate(III) Anion." Angewandte Chemie International Edition 57.34 (2018): 10999-11003.
description	12.	Tolbert, L. "Stereoelectronic effects in the deprotonation of arylalkyl radical cations: meso-ethylanthracenes." Journal of the American Chemical Society 112.6 (1990): 2373-2378.
description	13.	Arnold, D. "Synthesis and biological activity of a focused library of mitogen-activated protein kinase phosphatase inhibitors." Chemical biology & drug design 69.1 (2007): 23-30.
description	14.	Prieto, M. "Racemization in Suzuki couplings: A quantitative study using 4-hydroxyphenylglycine and tyrosine derivatives as probe molecules." Journal of organic chemistry 72.3 (2007): 1047-1050.
description	15.	OLSEN, A. "FIBRONECTIN BINDING MEDIATED BY A NOVEL CLASS OF SURFACE ORGANELLES ON ESCHERICHIA-COLI." Nature 338.6217 (1989): 652-655.
description	16.	Cegelski, L. "The biology and future prospects of antivirulence therapies." Nature reviews. Microbiology 6.1 (2008): 17-27.
description	17.	Seebach, D. "Helices and other secondary structures of Î²- and Î³-peptides." Biopolymers 84.1 (2006): 23-37.
description	18.	Tam, J. "Methods and strategies of peptide ligation." Biopolymers 60.3 (2001): 194-205.
description	19.	Lipschutz, M E E. "Geochemical and cosmochemical materials." Analytical chemistry 79.12 (2007): 2797-4274.
description	20.	Yeh, In-Chul C. "Nucleic acid transport through carbon nanotube membranes." Proceedings of the National Academy of Sciences of the United States of America 101.33 (2004): 12177-12182.