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Title:	Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of Parkinson’s Disease
Source:	Journal of Medicinal Chemistry [0022-2623] Jörg, Manuela yr:2014

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description	8.	Wang, Z. "Valproic acid-associated low fibrinogen and delayed intracranial hemorrhage: case report and mini literature review." Drug design, development and therapy 7 (2013): 767-770.
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description	11.	Borgman, Robert J. "Î±-Methyldopamine derivatives. Synthesis and pharmacology." Journal of medicinal chemistry 17.4 (1974): 427-.
description	12.	Herrmann, N. "Current and emerging drug treatment options for Alzheimer's disease: a systematic review.(Report)." Drugs 71.15 (2011): 2031-.
description	13.	Dias, Raquel B. "Enhancement of AMPA currents and GluR1 membrane expression through PKA-coupled adenosine A2A receptors." Hippocampus 22.2 (2010): 276-291.
description	14.	Zhu, Y. "Synthesis, in Vitro and in Vivo Biological Evaluation, and Comprehensive Understanding of Structure-Activity Relationships of Dipeptidyl Boronic Acid Proteasome Inhibitors Constructed from beta-Amino Acids." Journal of medicinal chemistry 53.24 (2010): 8619-8626.
description	15.	Schrader, J. "Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices." Neuropharmacology 33.9 (1994): 1049-1053.
description	16.	PORTOGHESE, PS. "OPIOID AGONIST AND ANTAGONIST BIVALENT LIGANDS AS RECEPTOR PROBES." Life sciences 31.12-1 (1982): 1283-1286.
description	17.	MAL, D. "Regiospecific synthesis of 3-(2,6-dihydroxyphenyl)phthalides: application to the synthesis of isopestacin and cryphonectric acid." Tetrahedron 63.47 (2007): 11781-11792.
description	18.	Schwerin, M. "Stress-related gene expression in brain and adrenal gland of porcine fetuses and neonates." Theriogenology 63.4: 1220-1234.
description	19.	Hibbert Edward G, Edward G. "Directed evolution of biocatalytic processes." Biomolecular engineering 22.1 (2005): 11-19.
description	20.	Pinnen, F. "Synthesis and study of L-dopa-glutathione codrugs as new anti-parkinson agents with free radical scavenging properties." Journal of medicinal chemistry 50.10 (2007): 2506-2515.