Background: Respiratory syncytial virus (RSV) is an important cause of childhood hospitalizations. The aim of the study was to estimate the rates of RSV-related hospitalizations in children aged less than 5 years in Poland. Methods: This retrospective observational cohort study was based on data obtained from the National Health Fund in Poland regarding all acute respiratory tract infections and RSV-coded admissions of children (age <5 years) to public hospitals between July 2015 and June 2023. Patients were stratified based on the following age groups: 0–1 month, 2–3 months, 4–6 months, 7–12 months, 13–24 months, and 25–60 months. Results: The number of RSV-related hospitalizations increased every season, both before and through the ending phase of the coronavirus disease 2019 (COVID-19) pandemic. The COVID-19 pandemic was associated with a shift in the seasonality pattern of RSV infection. Hospitalization rates per 1000 inhabitants were the highest for children aged 0–12 months, reaching 47.3 in the 2022/23 season. Within this group, the highest hospitalization rate was observed for children aged 2–3 months—94.9 in the 2022/23 season. During the ending phase of the COVID-19 pandemic, the observed increase in admission rates was 2-, 4-, and 5-fold the pre-COVID rate for children aged <12 months, 12–24 months, and 25–60 months, respectively. Conclusions: In Poland, RSV infections cause a significant burden in hospitalized children aged less than 5 years. RSV-related hospitalizations were most frequent in children aged less than 1 year. The COVID-19 pandemic was associated with a shift in the seasonality pattern of RSV infections. After the pandemic, more RSV-related hospitalizations were observed in older children (aged 13 months and older) vs. the pre-pandemic phase. Full article

The aging of semiconductor materials is a topic of current interest. We studied the photo-response of epitaxial samples of GaAs doped with Ge and Sn up to 1 × 10¹⁹ atoms cm⁻³. These samples were stored in a dry and dark environment for 26 years. We realized photoluminescence measurements at different temperatures and photoreflectance spectra at 300 K in three periods: 1995, 2001 and 2021. We found that environmental oxygen formed defects in GaAs, leaving lattice vacancies that provoked changes in the optical photo-response. In addition, we found that the vacancy concentrations could be as large as 5 × 10¹⁷ atoms cm⁻³ over the 26 years. In this work, we demonstrate that the aging of semiconductor materials occurs even when they are not used within a functioning circuit, with the changes being greater when the material is not doped. Knowing about the aging of materials is important for the industry, particularly for the semiconductor industry, because aging-induced deterioration influences prices and guarantees. Full article

Marine water quality significantly impacts human livelihoods and production such as fisheries, aquaculture, and tourism. Satellite remote sensing facilitates the predictions of large-area marine water quality without the need for frequent field work and sampling. Prediction of diffuse attenuation coefficient (Kd), which describes the speed at which light decays as it travels through water, obtained from satellite-derived ocean color products can reflect the overall water quality trends. However, current models inadequately explore the complex nonlinear features of Kd, and there are difficulties in achieving accurate long-term predictions and optimal computational efficiency. This study innovatively proposes a model called Remote Sensing-Informer-based Kd Prediction (RSIKP). The proposed RSIKP is characterized by a distinctive Multi-head ProbSparse self-attention mechanism and generative decoding structure. It is designed to comprehensively and accurately capture the long-term variation characteristics of Kd in complex water environments while avoiding error accumulation, which has a significant advantage in multi-dataset experiments due to its high efficiency in long-term prediction. A multi-dataset experiment is conducted at different prediction steps, using 70 datasets corresponding to 70 study areas in Hangzhou Bay and Beibu Gulf. The results show that RSIKP outperforms the five prediction models based on Artificial Neural Networks (ANN, Convolutional Neural Networks (CNN), Gated Recurrent Unit (GRU), Long Short-Term Memory Recurrent Neural Networks (LSTM-RNN), and Long Short-Term Memory Networks (LSTM)). RSIKP captures the complex influences on Kd more effectively to achieve higher prediction accuracy compared to other models. It shows a mean improvement of 20.6%, 31.1%, and 22.9% on Mean Absolute Error (MAE), Mean Square Error (MSE), and Mean Absolute Percentage Error (MAPE). Particularly notable is its outstanding performance in the long time-series predictions of 60 days. This study develops a cost-effective and accurate method of marine water quality prediction, providing an effective prediction tool for marine water quality management. Full article

HgCdTe is a well-known material for state-of-the-art infrared photodetectors. The interd-iffused multilayer process (IMP) is used for Metal–Organic Chemical Vapor Deposition (MOCVD) of HgCdTe heterostructures, enabling precise control of composition. In this method, alternating HgTe and CdTe layers are deposited, and they homogenize during growth due to interdiffusion, resulting in a near-uniform material. However, the relatively low (350 °C) IMP MOCVD growth temperature may result in significant residual compositional inhomogeneities. In this work, we have investigated the residual inhomogeneities in the IMP-grown HgCdTe layers and their influence on material properties. Significant IMP growth-related oscillations of composition have been revealed in as-grown epilayers with the use of a high-resolution Secondary Ion Mass Spectroscopy (SIMS). The oscillations can be minimized with post-growth annealing of the layers at a temperature exceeding that of growth. The electric and photoelectric characterizations showed a significant reduction in the background doping and an increase in the recombination time, which resulted in dramatic improvement of the spectral responsivity of photoconductors. Full article

The article presents the analysis, design, and low-cost implementation of application-specific AD converters for M-sequence-based UWB applications to minimize and integrate the whole UWB sensor system. Therefore, the main goal of this article is to integrate the AD converter’s own design with the UWB analog part into the system-in-package (SiP) or directly into the system-on-a-chip (SoC), which cannot be implemented with commercial AD converters, or which would be disproportionately expensive. Based on the current and used UWB sensor system requirements, to achieve the maximum possible bandwidth in the proposed semiconductor technology, a parallel converter structure is designed and presented in this article. Moreover, 5-bit and 4-bit parallel flash AD converters were initially designed as part of the research and design of UWB M-sequence radar systems for specific applications, and are briefly introduced in this article. The requirements of the newly proposed specific UWB M-sequence systems were established based on the knowledge gained from these initial designs. After thorough testing and evaluation of the concept of the early proposed AD converters for these specific UWB M-sequence systems, the design of a new AD converter was initiated. After confirming sufficient characteristics based on the requirements of UWB M-sequence systems for specific applications, a 7-bit AD converter in low-cost 0.35 µm SiGe BiCMOS technology from AMS was designed, fabricated, and presented in this article. The proposed 7-bit AD converter achieves the following parameters: ENOB = 6.4 bits, SINAD = 38 dB, SFDR = 42 dBc, INL = ±2-bit LSB, and DNL = ±1.5 LSB. The maximum sampling rate reaches 1.4 Gs/s, the power consumption at 20 Ms/s is 1050 mW, and at 1.4 Gs/s is 1290 mW, with a power supply of −3.3 V. Full article

The Dominican theologian Durand of Saint-Pourçain (ca. 1275–1334), breaking from the wide consensus, made a two-pronged attack on concurrentism (i.e., the theory according to which God does more than conserving creatures in existence and co-causes all their actions). On the one hand, he shows that the concurrentist position leads to the unacceptable consequence that God is the direct cause of man’s evil actions. On the other hand, he attacks the metaphysical foundations of concurrentism, first in the version offered by Thomas Aquinas and Giles of Rome, and then in a more general way. Against Thomas and Giles, he challenges Neoplatonic assumptions about causality and being. More generally, he establishes that God’s action and a creature’s action can be neither identical nor different, and thus cannot both be direct causes of the same effect. Without claiming that Durand’s series of objections are definitely unanswerable, we may at least observe that they have generally been underestimated (which earned him the lowly role of the mere foil of the concurrentist view in the history of philosophy) and are able to do considerable damage to concurrentism. Full article

This study experimentally investigates the influence of metal chips and glass fibers on the mode I fracture toughness, energy absorption, and tensile strength of polymer concretes (PCs) manufactured by waste aggregates. A substantial portion of the materials employed in manufacturing and enhancing the tested polymer concrete are sourced from waste material. To achieve this, semi-circular bend (SCB) samples were fabricated, both with and without a central crack, to analyze the strength and fracture behavior of the composite specimens. The specimens incorporated varying weight percentages comprising 50 wt% coarse mineral aggregate, 25 wt% fine mineral aggregate, and 25 wt% epoxy resin. Metal chips and glass fibers were introduced at 2, 4, and 8 wt% of the PC material to enhance its mechanical response. Subsequently, the specimens underwent 3-point bending tests to obtain tensile strength, mode I fracture toughness, and energy absorption up to failure. The findings revealed that adding 4% brass chips along with 4% glass fibers significantly enhanced energy absorption (by a factor of 3.8). However, using 4% glass fibers alone improved it even more (by a factor of 10.5). According to the results, glass fibers have a greater impact than brass chips. Introducing 8% glass fibers enhanced the fracture energy by 92%. However, in unfilled samples, aggregate fracture and separation hindered crack propagation, and filled samples presented added barriers, resulting in multiple-site cracking. Full article

(1) Background: The literature regarding orthorexia nervosa (ON) has well documented the association with other mental disorders, such as obsessive–compulsive and eating disorders. However, the research has not taken into account stress-related behavior and the conduction of physical activity (PA), both structured and unstructured. (2) Methods: In this cross-sectional study, 165 students of the University of Parma (92 females and 74 males) aged between 18 and 49 years old (mean = 24.62 ± 4.81) were consecutively recruited. The ORTO-15 questionnaire was used to divide the total sample into a group without orthorexia (score > 40) and a group with orthorexia (score < 40). All subjects completed the P Stress Questionnaire, and specific items were extrapolated from the Eating Habits Structured Interview (EHSI) to investigate lifestyle, including structured and unstructured PA. (3) Results: Subjects with orthorexia represented 83% of the total sample and reported higher levels of stress-related risk behaviors (i.e., sense of responsibility (t = −1.99, p = 0.02), precision (t = −1.99, p = 0.03), stress disorders (t = −1.38, p = 0.05), reduced spare time (t = −1.97, p = 0.03), and hyperactivity (t = −1.68, p = 0.04)) and a higher frequency of PA (i.e., hours spent training in structured PA, daily (t = −1.68, p = 0.05), weekly (t = −1.91, p = 0.03), and monthly (t = −1.91, p = 0.03), the tendency to carry out physical exercise even if tired (t = −1.97, p = 0.02), and to adhere to unstructured PA (i.e., moving on foot or by bike rather than using transport (t = 1.27, p = 0.04)). (4) Conclusions: The results confirmed the presence of hyperactivity at a motor and behavioral level in people with orthorexia. Further studies are necessary to highlight the causality between ON, stress, and physical activity but it may be possible to hypothesize that “obsessive” physical exercise may not generate the benefits generally known by the literature. Full article

The presence of periodontal pathogens is associated with an increased prevalence of rheumatoid arthritis (RA). The systemic antibody response to epitopes of these bacteria is often used as a proxy to study correlations between bacteria and RA. The primary aim of the present study is to examine the correlation between the presence of Aggregatibacter actinomycetemcomitans (Aa) in the oral cavity and serum antibodies against the leukotoxin (LtxA) produced by this bacterium. The salivary presence of Aa was analyzed with quantitative PCR and serum LtxA ab in a cell culture-based neutralization assay. The analyses were performed on samples from a well-characterized RA cohort (n = 189) and a reference population of blood donors (n = 101). Salivary Aa was present in 15% of the RA patients and 6% of the blood donors. LtxA ab were detected in 19% of RA-sera and in 16% of sera from blood donors. The correlation between salivary Aa and serum LtxA ab was surprisingly low (rho = 0.55 [95% CI: 0.40, 0.68]). The presence of salivary Aa showed no significant association with any of the RA-associated parameters documented in the cohort. A limitation of the present study is the relatively low number of individuals with detectable concentrations of Aa in saliva. Moreover, in the comparison of detectable Aa prevalence between RA patients and blood donors, we assumed that the two groups were equivalent in other Aa prognostic factors. These limitations must be taken into consideration when the result from the study is interpreted. We conclude that a systemic immune response to Aa LtxA does not fully reflect the prevalence of Aa in saliva. In addition, the association between RA-associated parameters and the presence of Aa was negligible in the present RA cohort. Full article

Pediatric patients who undergo implant insertion into the chest wall face a high risk of implant exposure to the external environment. Five months after an 8-year-old boy underwent implantable cardioverter–defibrillator (ICD) implantation in a subcutaneous pocket in the left anterolateral chest wall to manage long QT syndrome, ICD replacement became necessary owing to exposure risk from distal and lateral thinning of the ICD pocket. Pocket rupture and exposure would increase the risk of infection; therefore, we performed ICD removal and primary pocket closure. Two weeks later, a new suprafascial pocket was created, an acellular dermal matrix (ADM) was attached to the inner wall to prevent ICD protrusion, and a new ICD was inserted. One year postoperatively, the ADM was engrafted, and no complications were observed. A thin subcutaneous layer increases the risk of ICD implantation complications. Inner wall strengthening with an ADM can help prevent pocket rupture. Full article

This study introduces a newly modified Lorenz model capable of demonstrating bifurcation within a specified range of parameters. The model demonstrates various bifurcation behaviors, which are depicted as distinct structures in the diagram. The study aims to discover and analyze the existence and stability of fixed points in the model. To achieve this, the center manifold theorem and bifurcation theory are employed to identify the requirements for pitchfork bifurcation, period-doubling bifurcation, and Neimark–Sacker bifurcation. In addition to theoretical findings, numerical simulations, including bifurcation diagrams, phase pictures, and maximum Lyapunov exponents, showcase the nuanced, complex, and diverse dynamics. Finally, the study applies the Ott–Grebogi–Yorke (OGY) method to control the chaos observed in the reduced modified Lorenz model. Full article

The riparian vegetation buffer zone plays an important role in the prevention and control of non-point source pollution, and consideration should be given to selecting one with a lower cost and better effect. The SWAT model was used to simulate the regulation ability of riparian vegetation buffer zone layout on runoff, nitrogen, and phosphorus in the Jiawang Basin, and five different vegetation buffer zone layout scenarios were set up. The results showed that (1) the SWAT model has good applicability in simulating runoff and water quality in the Jiawang Basin; (2) the reduction rates of runoff, total nitrogen, and total phosphorus in continuous forest riverbank buffer zones reached 2.46%, 6.63%, and 9.18%, and their regulatory effects were better than those in grasslands; (3) there is not much difference in the inhibitory effect of forest and grassland on total nitrogen, but the discontinuous forest buffer zone has a better reduction effect on total phosphorus than grassland. Therefore, in the actual arrangement of vegetation buffer zones, it should be tailored to local conditions to achieve ideal non-point source pollution prevention and control effects at a lower cost. Full article

Sortase A (SrtA) is responsible for anchoring surface proteins to the cell wall, and has been identified as a promising target developing anti-infective drugs of Gram-positive bacteria. The aim of the study was to identify inhibitors of Streptococcus agalactiae (S. agalactiae) SrtA from natural compounds to overcome the spread of antibiotic resistance in aquaculture. Here, we found that the MIC of fraxetin against S. agalactiae was higher than 256 μg/mL, indicating that fraxetin had no anti- S. agalactiae activity. But fraxetin could dose-dependently decrease the activity of SrtA in vitro at concentrations ranging between 4–32 μg/mL by a fluorescence resonance energy transfer (FRET) assay. Moreover, the inhibition of SrtA by fraxetin decreased the anchoring of surface proteins with the LPXTG motif to the cell wall by detecting the immunofluorescence change of serine-rich repeat protein 1 (Srr1) on the bacterial cell surface. The results of fibronectin binding and cell adhesion assays indicated that fraxetin could significantly decrease the adhesion ability of S. agalactiae in a dose-dependent manner. The results were further proven by immunofluorescence staining. Animal challenge results showed that treatment with fraxetin could reduce the mortality of tilapia infected with S. agalactiae to 46.67%, indicating that fraxetin could provide a significant amount of protection to tilapia by inactivating SrtA. Taken together, these findings provided a novel inhibitor of S. agalactiae SrtA and a promising candidate for treating S. agalactiae infections in aquaculture. Full article

Objectives: Radiomics and machine learning are innovative approaches to improve the clinical management of NSCLC. However, there is less information about the additive value of FDG PET-based radiomics compared with clinical and imaging variables. Methods: This retrospective study included 320 NSCLC patients who underwent PET/CT with FDG at initial staging. VOIs were placed on primary tumors only. We included a total of 94 variables, including 87 textural features extracted from PET studies, SUVmax, MTV, TLG, TNM stage, histology, age, and gender. We used the least absolute shrinkage and selection operator (LASSO) regression to select variables with the highest predictive value. Although several radiomics variables are available, the added value of these predictors compared with clinical and imaging variables is still under evaluation. Three hundred and twenty NSCLC patients were included in this retrospective study and underwent 18F-FDG PET/CT at initial staging. In this study, we evaluated 94 variables, including 87 textural features, SUVmax, MTV, TLG, TNM stage, histology, age, and gender. Image-based predictors were extracted from a volume of interest (VOI) positioned on the primary tumor. The least absolute shrinkage and selection operator (LASSO) Cox regression was used to reduce the number of variables and select only those with the highest predictive value. The predictive model implemented with the variables selected using the LASSO analysis was compared with a reference model using only a tumor stage and SUVmax. Results: NGTDM coarseness, SUVmax, and TNM stage survived the LASSO analysis and were used for the radiomic model. The AUCs obtained from the reference and radiomic models were 80.82 (95%CI, 69.01–92.63) and 81.02 (95%CI, 69.07–92.97), respectively (p = 0.98). The median OS in the reference model was 17.0 months in high-risk patients (95%CI, 11–21) and 113 months in low-risk patients (HR 7.47, p < 0.001). In the radiomic model, the median OS was 16.5 months (95%CI, 11–20) and 113 months in high- and low-risk groups, respectively (HR 9.64, p < 0.001). Conclusions: Our results indicate that a radiomic model composed using the tumor stage, SUVmax, and a selected radiomic feature (NGTDM_Coarseness) predicts survival in NSCLC patients similarly to a reference model composed only by the tumor stage and SUVmax. Replication of these preliminary results is necessary. Full article

The therapeutic options for hepatocellular carcinoma (HCC) have greatly expanded recently, and current first-line therapies include sorafenib, lenvatinib, and atezolizumab-bevacizumab. The aim of this study was to investigate the therapeutic efficacy of sequential systemic treatments after progressing to the first-line agent in patients with unresectable HCC. Methods: Data were collected from subjects with HCC, BCLC stage B or C, who received first-line sorafenib, lenvatinib, or atezolizumab-bevacizumab from September 2020 to December 2022. The patients who progressed after first-line therapy were evaluated according to individual clinical status in order to decide whether or not to accept sequential therapy. The clinical baseline characteristics and overall survival (OS) of enrolled patients were collected and further analyzed. Results: Among the 127 enrolled patients, percentage of sequential therapy was 67.9%, 21.6%, and 37.5% in those with tumor progression after first-line sorafenib, lenvatinib, or atezolizumab-bevacizumab, respectively. Acceptance of sequential therapy (HR 0.46, p = 0.041) and presentation of ALBI grade I (HR 0.36, p=0.002) had a significantly positive impact on OS. Pre-treatment ALBI grade had a significant impact on the decision to accept sequential therapy in patients with progressed HCC. Conclusions: The patients who were able to undergo sequential therapy had a better survival outcome compared to those who received only one agent, and the pre-treatment ALBI level might be regarded as a cornerstone tool to assess survival outcomes in patients undergoing treatment for HCC. Full article

The growing interest in “Traineras”, a traditional competitive rowing modality prevalent in Northern Spain, underscores the need for a comprehensive analysis of the injury incidence associated with this sporting practice. Despite rowing’s significance in the international sports arena and its inclusion since the beginnings of the modern Olympic Games, research into injuries in this sport, especially in traditional modalities such as Traineras, has been limited. This study aimed to identify and describe the predominant injuries among Traineras rowers, analyzing their epidemiology, characteristics, affected body regions, and diagnoses, further differentiated by competitive level and gender. A retrospective survey completed by 773 rowers (24% women, 76% men) participating in various leagues (ACT, ARC1, ARC2, LGT1, LGT2, ETE, and LGT-F) during the season revealed that 68.2% suffered from at least one injury, predominantly due to overuse (91.1% in men, 83.1% in women). The most affected regions were the lower back and shoulders, with the main diagnoses being muscle cramps and tendinitis, showing statistically significant differences between sexes. The findings of this study not only provide a deeper understanding of the etiology and origin of injuries in this sport but also lay the groundwork for developing specific injury prevention plans, thereby contributing to the safety and optimal performance of athletes. Full article

This study introduces an innovative approach to tackle multi-objective linear programming (MOLP) problems amidst uncertainty, employing interval-valued fuzzy numbers. The method is tailored to resolve ride-hailing matching challenges encompassing uncertain travel times. Findings reveal that managing uncertainty parameters within interval-valued fuzzy MOLP is achieved through strategic reformulations, focusing on constraint coefficients, resulting in streamlined linear programming formulations conducive to solution simplicity. The efficacy of the proposed model in efficiently handling ride-hailing matching quandaries is demonstrated. Moreover, this study delves into the prospective applications of the developed method, including its potential for generalization to address non-linear programming (NLP) issues pertinent to the ride-hailing domain. This research advances decision-making processes under uncertainty and paves the way for broader applications beyond ride-hailing. Full article

The firefighting protective suits (FPSs) of firefighters at fire scenes affect their health and safety. However, the association between firefighters’ health awareness of occupational exposure risks and the FPS use, washing and management remains unclear. Therefore, this study aimed to evaluate the association between firefighters’ health awareness of occupational exposure risks and their recognition, behaviors regarding the use, washing and management of FPSs. This study design is a cross-sectional study and used a web-based survey of the Seoul Metropolitan Government’s electronic survey system. The survey was conducted on metropolitan firefighters performing shift work in charge of fire and rescue work for 21 days from 1 to 22 April 2019, with 1097 (40.3%) respondents. Characteristics of FPS use, washing and management and the association between thoughts and behaviors thereof and health awareness of occupational exposure risks were evaluated. Data of 1097 firefighters were analyzed using the SAS 9.4 statistical package, chi-square test and logistic regression analysis. Firefighters’ fire scene awareness rate of possible carcinogens was 94.4%. There was an association between public health thinking of occupational exposure risks and the correct use of an FPS for one’s own safety (AOR 1.97. 95% CI 1.02–3.80). However, no association was shown between correct FPS use (AOR 1.49, 95% CI 0.48–4.59), washing (AOR 2.50, 95% CI 0.93–6.68) and management (AOR 1.38, 95% CI 0.75–2.50) behaviors. This study analyzed the relationship between the use, washing and management of personal protective equipment called firefighting clothing and firefighters perceived occupational exposure risks. This study found an association between the health awareness of occupational exposure risks and recognition of the correct use of FPSs at fire scenes but not between using, washing and managing behaviors of FPSs. This study is the first to analyze the relationship between firefighting clothing and occupational health awareness level. The results confirm that future interventions are required to help firefighters practice desirable behaviors toward FPSs and provided evidenced data for preventing occupational diseases among firefighters. Therefore, this study can be used to develop a firefighter occupational health curriculum and establish health and safety plans from mid- to long-term perspectives for firefighters’ safety against occupational exposure risks. Full article

With the increasing demand for energy and the depletion of traditional resources, the development of alternative energy sources has become a critical issue. Shale gas, as an abundant and widely distributed resource, has great potential as a substitute for conventional natural gas. However, due to the low permeability of shale-gas reservoirs, efficient extraction poses significant challenges. The application of hydraulic fracturing technology has been proven to effectively enhance rock permeability, but the influence of environmental factors on its efficiency remains unclear. In this study, we investigate the impact of gas fracturing on shale-gas extraction efficiency under varying environmental conditions using numerical simulations. Our simulations provide a comprehensive analysis of the physical changes that occur during the fracturing process, allowing us to evaluate the effects of gas fracturing on rock mechanics and permeability. We find that gas fracturing can effectively induce internal fractures within the rock, and the magnitude of tensile stress decreases gradually during the process. The boundary pressure of the rock mass is an important factor affecting the effectiveness of gas fracturing, as it exhibits an inverse relationship with the gas content present within the rock specimen. Furthermore, the VL constant demonstrates a direct correlation with gas content, while the permeability and PL constant exhibit an inverse relationship with it. Our simulation results provide insights into the optimization of gas fracturing technology under different geological parameter conditions, offering significant guidance for its practical applications. Full article

We introduce an innovative theoretical framework tailored for the analysis of Pair Distribution Function (PDF) data derived from Small-Angle X-ray Scattering (SAXS) measurements of core-shell micelles. The new approach involves the exploitation of the first derivative of the PDF and the derivation of analytical equations to solve the core-shell micelle structure under the hypothesis of a spheroidal shape. These analytical equations enable us to determine the micelle’s aggregation number, degree of ellipticity, and contrast in electron density between the core-shell and shell-buffer regions after having determined the whole micelle size and its shell size from the analysis of the first derivative of the PDF. We have formulated an overdetermined system of analytical equations based on the unknowns that characterize the micelle structure. This allows us to establish a Figure of Merit, which is utilized to identify the most reliable solution within the system of equations. Full article

SAR imagery plays a crucial role in geological and environmental monitoring, particularly in highland mountainous regions. However, inherent geometric distortions in SAR images often undermine the precision of remote sensing analyses. Accurately identifying and classifying these distortions is key to analyzing their origins and enhancing the quality and accuracy of monitoring efforts. While the layover and shadow map (LSM) approach is commonly utilized to identify distortions, it falls short in classifying subtle ones. This study introduces a novel LSM ground-range slope (LG) method, tailored for the refined identification of minor distortions to augment the LSM approach. We implemented the LG method on Sentinel-1 SAR imagery from the tri-junction area where the Xiaojiang, Pudu, and Jinsha rivers converge at the Yunnan-Sichuan border. By comparing effective monitoring-point densities, we evaluated and validated traditional methods—LSM, R-Index, and P-NG—against the LG method. The LG method demonstrates superior performance in discriminating subtle distortions within complex terrains through its secondary classification process, which allows for precise and comprehensive recognition of geometric distortions. Furthermore, our research examines the impact of varying slope parameters during the classification process on the accuracy of distortion identification. This study addresses significant gaps in recognizing geometric distortions and lays a foundation for more precise SAR imagery analysis in complex geographic settings. Full article

Outbreaks caused by foot-and-mouth disease (FMD) A/ASIA/G-VII lineage viruses have often occurred in Middle Eastern and Southeast Asian countries since 2015. Because A/ASIA/G-VII lineage viruses are reported to have distinct antigenic relatedness with available commercial FMD vaccine strains, it is necessary to investigate whether inoculation with vaccines used in Korea could confer cross-protection against A/ASIA/G-VII lineage viruses. In the present study, we conducted two vaccination challenge trials to evaluate the efficacy of three commercial FMD vaccines (O/Manisa + O/3039 + A/Iraq, O/Campos + A/Cruzeiro + A/2001, and O/Primorsky + A/Zabaikalsky) against heterologous challenge with ASIA/G-VII lineage viruses (A/TUR/13/2017 or A/BHU/3/2017 strains) in pigs. In each trial, clinical signs, viremia, and salivary shedding of virus were measured for 7 days after challenge. In summary, the O/Campos + A/Cruzeiro + A/2001 vaccine provided full protection against two A/ASIA/G-VII lineage viruses in vaccinated pigs, where significant protection was observed. Although unprotected animals were observed in groups vaccinated with O/Manisa + O/3039 + A/Iraq or O/Primorsky + A/Zabaikalsky vaccines, the clinical scores and viral RNA levels in the sera and oral swabs of vaccinated animals were significantly lower than those of unvaccinated controls. Full article