Zero-shot event detection aims to involve the automatic discovery and classification of new events within unstructured text. Current zero-shot event detection methods have not considered addressing the problem more effectively from the perspective of improving event representations. In this paper, we propose dual-contrastive prompting (COPE) model for learning event representations to address zero-shot event detection, which leverages prompts to assist in generating event embeddings using a pretrained language model, and employs a contrastive fusion approach to capture complex interaction information between trigger representations and sentence embeddings to obtain enhanced event representations. Firstly, we introduce a sample generator to create ordered contrastive sample sequences with varying degrees of similarity for each event instance, aiding the model in better distinguishing different types of events. Secondly, we design two distinct prompts to obtain trigger representations and event sentence embeddings separately. Thirdly, we employ a contrastive fusion module, where trigger representations and event sentence embeddings interactively fuse in vector space to generate the final event representations. Experiments show that our model is more effective than the most advanced methods. Full article

Shale is composed of a rock matrix and bedding planes with a layered structure, resulting in significant anisotropy in its mechanical properties. In order to study the anisotropic mechanical properties of shale, the shale samples were prepared in different orientations with respect to the bedding planes, and the composition and microstructure of shale were first analyzed by X-ray diffractometer (XRD) and scanning electron microscope (SEM), and then the uniaxial and triaxial compression experiment on shale samples with five different bedding angles (the angle between the loading direction and the normal direction of the bedding planes, 0°, 30°, 45°, 60°, and 90°) were conducted under five confining pressures (0, 10, 20, 30, and 40 MPa), respectively; meanwhile, the acoustic emission (AE) test was carried out in the uniaxial test. The results indicate that the mechanical properties and parameters of shale have obvious anisotropy, and the AE characteristics of shale samples with different bedding angles are significantly different during uniaxial loading. Furthermore, the compressive strength and elastic modulus of the shale samples first decrease and then increase with the increase in the bedding angle under different confining pressures. Moreover, according to the anisotropic grade of compressive strength, the shale has moderate anisotropy. In addition, the failure mode of the shale samples is also anisotropic, and varies with the bedding angle and confining pressure. Full article

This review examines the 15-year presence of mycotoxins in food from Serbia and Croatia to provide a comprehensive overview of trends. Encompassing the timeframe from 2009 to 2023, this study integrates data from both countries and investigates climate change patterns. The results from Serbia focus primarily on maize and milk and show a strong dependence of contamination on weather conditions. However, there is limited data on mycotoxins in cereals other than maize, as well as in other food categories. Conversely, Croatia has a broader spectrum of studies, with significant attention given to milk and maize, along with more research on other cereals, meat, and meat products compared to Serbia. Over the investigated 15-year period, both Serbia and Croatia have experienced notable shifts in climate, including fluctuations in temperature, precipitation, and humidity levels. These changes have significantly influenced agriculture, consequently affecting the occurrence of mycotoxins in various food products. The results summarized in this 15-year review indicate the urgent need for further research and action to address mycotoxin contamination in Serbian and Croatian food supply chains. This urgency is further emphasized by the changing climatic conditions and their potential to exacerbate public health and food safety risks associated with mycotoxins. Full article

Parkinson’s disease (PD) is recognized as the second most prevalent primary chronic neurodegenerative disorder of the central nervous system. Clinically, PD is characterized as a movement disorder, exhibiting an incidence and mortality rate that is increasing faster than any other neurological condition. In recent years, there has been a growing interest concerning the role of the gut microbiota in the etiology and pathophysiology of PD. The establishment of a brain–gut microbiota axis is now real, with evidence denoting a bidirectional communication between the brain and the gut microbiota through metabolic, immune, neuronal, and endocrine mechanisms and pathways. Among these, the vagus nerve represents the most direct form of communication between the brain and the gut. Given the potential interactions between bacteria and drugs, it has been observed that the therapies for PD can have an impact on the composition of the microbiota. Therefore, in the scope of the present review, we will discuss the current understanding of gut microbiota on PD and whether this may be a new paradigm for treating this devastating disease. Full article

In the summer of 2022, Pakistan experienced a severe flood event that brought great destruction to the local people and ecosystem. However, there is no comprehensive study on the process, spread and causes of this flood. Therefore, we combined multiple satellite gravity data, meteorological data, hydrological data, and satellite remote sensing data to conduct a thorough investigation and study of this flood. The results show that a 20-year time series of the terrestrial water storage change based multiple gravity data has the high accuracy and reliability, which is used for detecting the flood. The flood propagated through meteorological system (three months), agricultural system (six months) and terrestrial ecosystems (five months), respectively, and the two southern provinces (Balochistan and Sindh) are the most affected by the flood, whose flood severity is 6.955 and 9.557, respectively. The center of the severe flood is located at the border region between the above two province. The severe flood is attributed primarily to the global extreme climate events (La Niña and negative Indian Ocean Dipole events) that altered the transport path of water vapor in the Indian Ocean, causing large amounts of water vapor to converge over Pakistan, resulting in heavy precipitation, and secondarily to the melting of extensive glacier in the mountainous of northern Pakistan as a result of the high temperature in March-May 2022. The above results contribute to the understanding of the mechanism of the impact of extreme climate events on the regional climate, and provide some references for the study of severe floods. Full article

Endophytic fungi that reside internally in healthy, asymptomatic plants often benefit their hosts by promoting plant growth and/or providing plant protection against abiotic and biotic stresses. However, only a small fraction of the estimated 1.5 million fungal endophytes have been identified. In this study, a total of 369 isolates of fungal endophytes in 59 distinct taxa were isolated from stem samples of Cornus florida (flowering dogwood). All isolates belonged to species of phyla Ascomycota and Basidiomycota distributed across five orders and 11 genera. Isolates belonging to the same family clustered together in a phylogenetic tree generated from a cluster analysis using MEGA 7 software. Diversity indices of the fungi revealed a rich and diverse community that included several species associated with leaf spots, blight, cankers, and/or dieback diseases. Pathogenicity tests confirmed 16 fungal endophytes as C. florida pathogens, including some well-known destructive pathogens Botryosphaera dothidea, Colletotrichum acutatum, and C. gleosporoides. Isolates of the fungal endophytes possess the capacity to produce extracellular hydrolytic enzymes (cellulase, amylase, pectinase, laccase, chitinase, and protease) that are known to function in tissue penetration, plant colonization, nutrient acquisition, and disease suppression in both plant pathogens and endophytes These results support the interchangeable pathogenic–endophytic roles for some taxa. Full article

According to the recent revision of the Greek National Energy and Climate Plan, the country sets out to accomplish an ambitious target concerning the integration of renewables in the local electricity mix during the ongoing decade, at the levels of 80% by 2030. This implies the need to more than double the existing wind and PV capacity at the national level, which in turn introduces numerous challenges. Amongst them, spatial planning for new RES installations seems to be the most demanding, with the adoption of novel technological solutions in the field of RES potentially holding a key role. New technologies, like offshore wind and floating solar, are gradually gaining maturity and may offer such an alternative, challenged at the same time however by the need to entail minimum disruption for local ecosystems. To that end, we currently assess the theoretical potential of floating PVs for lentic water systems of the Greek mainland. We do so by looking into 53 different lentic water systems across the Greek territory that meet the constraint of 1 km² minimum surface area, and we proceed with the estimation of the relevant floating PV capacity per system under the application of a minimal intervention approach, assuming PV coverage of 1% over the total lentic water system area. In this context, our findings indicate a maximum, aggregate theoretical capacity that could exceed 2 GW_p at the national level, with the respective annual energy yield reaching approximately 4 TWh or, equivalently, >6% of the country’s anticipated annual electricity consumption in 2030. Finally, our results extend further, offering a regional level analysis and a set of policy directions and considerations on the development of floating solar in Greece, while also designating the energy merits of floating PVs against similar, land-based installations. Full article

The development of multiple-drug-resistant (MDR) cancer all too often signals the need for alternative toxic therapy or palliative care. Our recent in vivo and in vitro studies using canine MDR lymphoma cancer cells demonstrate that the Anaphase Promoting Complex (APC) is impaired in MDR cells compared to normal canine control and drug-sensitive cancer cells. Here, we sought to establish whether this phenomena is a generalizable mechanism independent of species, malignancy type, or chemotherapy regime. To test the association of blunted APC activity with MDR cancer behavior, we used matched parental and MDR MCF7 human breast cancer cells, and a patient-derived xenograft (PDX) model of human triple-negative breast cancer. We show that APC activating mechanisms, such as APC subunit 1 (APC1) phosphorylation and CDC27/CDC20 protein associations, are reduced in MCF7 MDR cells when compared to chemo-sensitive matched cell lines. Consistent with impaired APC function in MDR cells, APC substrate proteins failed to be effectively degraded. Similar to our previous observations in canine MDR lymphoma cells, chemical activation of the APC using Mad2 Inhibitor-1 (M2I-1) in MCF7 MDR cells enhanced APC substrate degradation and resensitized MDR cells in vitro to the cytotoxic effects of the alkylating chemotherapeutic agent, doxorubicin (DOX). Using cell cycle arrest/release experiments, we show that mitosis is delayed in MDR cells with elevated substrate levels. When pretreated with M2I-1, MDR cells progress through mitosis at a faster rate that coincides with reduced levels of APC substrates. In our PDX model, mice growing a clinically MDR human triple-negative breast cancer tumor show significantly reduced tumor growth when treated with M2I-1, with evidence of increased DNA damage and apoptosis. Thus, our results strongly support the hypothesis that APC impairment is a driver of aggressive tumor development and that targeting the APC for activation has the potential for meaningful clinical benefits in treating recurrent cases of MDR malignancy. Full article

One of the most pressing issues in the implementation of construction projects is the extension of planned deadlines, significantly impacting project costs. This situation often arises due to inaccurate estimation of construction durations, which rely on normative values without accounting for factors hindering construction progress. Consequently, this article aims to develop an innovative approach for assessing construction durations, considering specific risk factors and their influence on construction activities. Given the difficulty of determining risk factors and their effects during the design phase using classical probability theory, characterized by unknown probability distributions, it is highlighted that this scenario represents planning and implementation under conditions of non-statistical uncertainty. Therefore, the article proposes an approach utilizing elements of fuzzy set theory, particularly fuzzy rules and linguistic variables, to determine delays in individual construction tasks. The proposed approach involves estimating extensions of construction timelines based on a specified probability level of occurrence for risk events and their impact. Additionally, the article provides a theoretical description of the proposed approach and practical calculation examples, demonstrating that the authors’ approach significantly enhances the accuracy of construction timeline forecasts, providing more reliable data for project planning and management. Full article

Background: Recently, minimally invasive access via right anterolateral mini-thoracotomy (RAMT) has been gaining popularity in cardiac surgery. This approach is also an option for surgeons performing aortic surgery. The aim of this study is to present our surgical method, highlighting the total endoscopic minimally invasive approach via RAMT for replacement of the ascending aorta (AAR) with or without involvement of the aortic root and the aortic valve. Methods: Clinical data of 44 patients from three participating institutions with AAR with or without involvement of the aortic valve or aortic root via RAMT between April 2017 and February 2024 were retrospectively analyzed. According to surgical procedure, patients were divided into two groups, in the AAR and in the Wheat/Bentall group with concomitant valve or root replacement. Operative time, length of ventilation, perioperative outcome, length of intensive care unit (ICU) as well as postoperative hospital stay, and mid- and long-term results were retrospectively analyzed. Results: Mean age was 61.4 ± 10.7 years old with a frequency of male gender of 63.6%. Mean cardiopulmonary bypass (CBP) time and aortic cross-clamping time was 94.9 ± 32.5 min and 63.8 ± 25.9 min, respectively. CPB and aortic clamp time were significantly lower in AAR group. In the first 24 h, the mean drainage volume was 790.3 ± 423.6 mL. Re-thoracotomy due to bleeding was zero. Sternotomy was able to be avoided in all patients. Patients stayed 35.9 ± 23.5 h at ICU and were discharged 7.8 ± 3.0 days following surgery from hospital. Mean ventilation time was 5.8 ± 7.6 h. All patients survived and 30-day mortality was 0.0%. At a median follow-up time of 18.2 months, all patients were alive. The results were similar in both groups. Conclusions: The full endoscopic RAMT approach with 3D visualization is a safe, feasible and promising technique that can be transferred in the field of aortic surgery without compromising surgical quality, postoperative outcomes, or patient safety when performed by an experienced team in a high-volume center. Full article

This paper considers the estimation of SOC and SOH for lithium batteries using multi-innovation Levenberg–Marquardt and adaptive weighting unscented Kalman filter algorithms. For parameter identification, the second-order derivative of the objective function to optimize the traditional gradient descent algorithm is used. For SOC estimation, an adaptive weighting unscented Kalman filter algorithm is proposed to deal with the nonlinear update problem of the mean and covariance, which can substantially improve the estimation accuracy of the internal state of the lithium battery. Compared with fixed weights in the traditional unscented Kalman filtering algorithm, this algorithm adaptively adjusts the weights according to the state and measured values to improve the state estimation update accuracy. Finally, according to simulations, the errors of this algorithm are all lower than 1.63 %, which confirms the effectiveness of this algorithm. Full article

A new approach is proposed that identifies three different zones of the Si-rich network structure (the cellular structure) in laser powder bed fused (LPBF) AlSi10Mg alloy, based on the variation in morphology, grain growth transition, and melt pool solidification conditions. The three identified zones are denoted in the present work as the liquid solidification zone (LSZ), the mushy solidification zone (MSZ), and the heat affected zone (HAZ). The LSZ is the result of liquid–solid transformation, showing small planar growth at the boundary and large cellular growth in the center, while the MSZ is related to a semisolid reaction, and the HAZ arises from a short-time aging process. The boundary between the LSZ and MSZ is identified by the change of grain growth direction and the Si-rich network advancing direction. The boundary between MSZ and HAZ is identified by the start of the breakdown of the Si-rich network. In addition, it is found that the fracture is generated in and propagates along the HAZ during tensile tests. Full article

Hylurgus ligniperda (Fabricius), a significant quarantine pest, has recently invaded China, marking a new spread outside its known global distribution. This study aims to clarify the invasion and colonization mechanisms of H. ligniperda in Shandong Province, a primary colonization site. This study employed sampling surveys and analysis of damaged wood, discovering that the wood-boring insects sharing the same host as H. ligniperda mainly include Cryphalus sp., Arhopalus rusticus, and Shirahoshizo sp. Through ecological niche theory, the study analyzed the ecological niche relationships between H. ligniperda and these three wood-boring insects, from the perspectives of temporal and spatial resource utilization. The results reveal that these insects could cause damage to P. thunbergii trees at different health levels, with H. ligniperda being the most destructive. The ecological niches of insect populations varied significantly by tree vigor and height. Cryphalus sp. occupied the entire trunk, whereas A. rusticus and Shirahoshizo sp. were concentrated in the lower-middle trunk and the root section up to a depth of 1 m. Notably, H. ligniperda primarily targeted tree roots. Due to the differences in spatial distribution, there was no intense competition between H. ligniperda and other wood-boring insects. With a decline in the health of the host tree, Cryphalus sp. ascended the trunk, whereas H. ligniperda spread deeper into the roots and A. rusticus moved towards the base of the trunk and the top of the roots. Shirahoshizo sp. showed a less defined distribution pattern. Therefore, H. ligniperda was more dominant during the later stage of damage. The position occupied by each insect on the trunk was relatively stable, and the ecological niche overlap value with H. ligniperda was low in terms of temporal resources. Therefore, H. ligniperda and other stem-boring pests exhibit coexisting populations mainly through the allocation and utilization of spatial resources, eventually promoting the successful colonization of H. ligniperda. Full article

Despite the extensive research successes and continuous developments in modern medicine in terms of diagnosis, prevention, and treatment, the lack of clinically useful disease-modifying drugs or immunotherapeutic agents that can successfully treat or prevent neurodegenerative diseases is an ongoing challenge. To date, only one of the 244 drugs in clinical trials for the treatment of neurodegenerative diseases has been approved in the past decade, indicating a failure rate of 99.6%. In corollary, the approved monoclonal antibody did not demonstrate significant cognitive benefits. Thus, the prevalence of neurodegenerative diseases is increasing rapidly. Therefore, there is an urgent need for creative approaches to identifying and testing biomarkers for better diagnosis, prevention, and disease-modifying strategies for the treatment of neurodegenerative diseases. Overexpression of the endogenous α-synuclein has been identified as the driving force for the formation of the pathogenic α-synuclein (α-Syn) conformers, resulting in neuroinflammation, hypersensitivity, endogenous homeostatic responses, oxidative dysfunction, and degeneration of dopaminergic neurons in Parkinson’s disease (PD). However, the conformational plasticity of α-Syn proffers that a certain level of α-Syn is essential for the survival of neurons. Thus, it exerts both neuroprotective and neurotoxic (regulatory) functions on neighboring neuronal cells. Furthermore, the aberrant metastable α-Syn conformers may be subtle and difficult to detect but may trigger cellular and molecular events including immune responses. It is well documented in literature that the misfolded α-Syn and its conformers that are released into the extracellular space from damaged or dead neurons trigger the innate and adaptive immune responses in PD. Thus, in this review, we discuss the nonintuitive plasticity and immunogenicity of the α-Syn conformers in the brain immune cells and their physiological and pathological consequences on the neuroimmune responses including neuroinflammation, homeostatic remodeling, and cell-specific interactions that promote neuroprotection in PD. We also critically reviewed the novel strategies for immunotherapeutic delivery interventions in PD pathogenesis including immunotherapeutic targets and potential nanoparticle-based smart drug delivery systems. It is envisioned that a greater understanding of the nonintuitive immunogenicity of aberrant α-Syn conformers in the brain’s microenvironment would provide a platform for identifying valid therapeutic targets and developing smart brain delivery systems for clinically effective disease-modifying immunotherapeutics that can aid in the prevention and treatment of PD in the future. Full article

The incidence of ulcerative colitis (UC) is increasing annually, and UC has a serious impact on patients’ lives. Polysaccharides have gained attention as potential drug candidates for treating ulcerative colitis (UC) in recent years. Huaier (Trametes robiniophila Murr) is a fungus that has been used clinically for more than 1000 years, and its bioactive polysaccharide components have been reported to possess immunomodulatory effects, antitumour potential, and renoprotective effects. In this study, we aimed to examine the protective effects and mechanisms of Huaier polysaccharide (HP) against UC. Based on the H₂O₂-induced oxidative stress model in HT-29 cells and the dextran sulphate sodium salt (DSS)-induced UC model, we demonstrated that Huaier polysaccharides significantly alleviated DSS-induced colitis (weight loss, elevated disease activity index (DAI) scores, and colonic shortening). In addition, HP inhibited oxidative stress and inflammation and alleviated DSS-induced intestinal barrier damage. It also significantly promoted the expression of the mucin Muc2. Furthermore, HP reduced the abundance of harmful bacteria Escherichia-Shigella and promoted the abundance of beneficial bacteria Muribaculaceae_unclassified, Anaerotruncus, and Ruminococcaceae_unclassified to regulate the intestinal flora disturbance caused by DSS. Nontargeted metabolomics revealed that HP intervention would modulate metabolism by promoting levels of 3-hydroxybutyric acid, phosphatidylcholine (PC), and phosphatidylethanolamine (PE). These results demonstrated that HP had the ability to mitigate DSS-induced UC by suppressing oxidative stress and inflammation, maintaining the intestinal barrier, and modulating the intestinal flora. These findings will expand our knowledge of how HP functions and offer a theoretical foundation for using HP as a potential prebiotic to prevent UC. Full article

Online retail platforms such as Amazon and Tmall have the ability to create personalized recommendations based on the consumer’s browsing history, purchase history, and preferences by investing in data analytics capability. In practice, manufacturers may encroach on the retail market through the agency channel that sells products directly to online consumers in addition to wholesale products to retail platforms through the reselling channel. In this study, we develop a game-theoretic model to study the interplay between the manufacturer’s encroachment and the online retail platform’s data analytics capability investment. Our outcomes reveal that the conditions for the manufacturer to encroach become more lenient if the platform invests in data analytics capability, and we show that the investment in data analytics capability can lead to a Pareto improvement and the manufacturer can free ride on the platform’s investment. Moreover, we found that the manufacturer’s encroachment always creates more incentives for the platform to enhance the investment level in data analytics capability. Our research in this study provides useful insights for managers to make encroachment decisions and data analytics capability investment decisions with the manufacturer who sells through the online retail platform. Full article

This study aimed to examine the mediating role of body image coping strategies in the relationship between positive body image and wellbeing. Three hundred and seventy-two women and three hundred and seventy-seven men completed a questionnaire assessing body appreciation, body appreciation functionality, body compassion, body image coping strategies (appearance fixing, avoidance, positive rational acceptance), self-acceptance and overall psychological wellbeing. Path analysis showed that avoidance significantly mediated the relationship between body appreciation and overall psychological wellbeing among both women and men; its mediating role was confirmed for men’s but not for women’s self-acceptance. Positive rational acceptance was a significant mediator of the relationship between body compassion and both psychological wellbeing and self-acceptance among men but not among women. These findings show that higher body appreciation is associated with a lower tendency to avoid appearance-related cognitions or thoughts that are interpreted as threatening, with an indirect effect on women’s and men’s psychological wellbeing. Analogously, but only for men, body compassion is associated with mental activities and self-care behaviors that foster rational self-talk and the acceptance of one’s experiences, which, in turn, are linked to higher wellbeing. These findings can help to plan programs aimed at fostering individuals’ wellbeing by focusing on their positive body image considering gender differences. Full article

Vibrio species are naturally found in estuarine and marine ecosystems, but are also recognized as significant human enteropathogens, often linked to seafood-related illnesses. In aquaculture settings, Vibrio poses a substantial risk of infectious diseases, resulting in considerable stock losses and prompting the use of antimicrobials. However, this practice contributes to the proliferation of antimicrobial-resistant (AMR) bacteria and resistance genes. Our investigation aimed to explore the potential of biological agents such as bacteriophage CH20 and endolysin LysVPp1 in reducing Vibrio bacterial loads in both rotifer and fish larvae. LysVPp1’s lytic activity was assessed by measuring absorbance reduction against various pathogenic Vibrio strains. Phage CH20 exhibited a limited host range, affecting only Vibrio alginolyticus GV09, a highly pathogenic strain. Both CH20 and LysVPp1 were evaluated for their effectiveness in reducing Vibrio load in rotifers or fish larvae through short-setting bioassays. Our results demonstrated the significant lytic effect of endolysin LysVPp1 on strains of Vibrio alginolyticus, Vibrio parahaemolyticus, and Vibrio splendidus. Furthermore, we have showcased the feasibility of reducing the load of pathogenic Vibrio in live feed and fish larvae by using a non-antibiotic-based approach, such as lytic phage and endolysin LysVPp1, thus contributing to the progress of a sustainable aquaculture from a One Health perspective. Full article

Many cities in coastal areas are prone to typhoon disasters due to their location on the Pacific storm path, and the direct effect of catastrophic winds can lead to the destruction of low-rise buildings and severe damage to high-rise structures. The purpose of this study was to enhance the understanding of boundary layer wind profiles of strong typhoons in coastal areas and reduce property losses and casualties caused by wind disasters. Based on the field measurements of wind profile acoustic radar in coastal areas, the variation characteristics of the boundary layer wind profile during the passage of super typhoon Lekima were first studied in depth, and the evolution law of the typhoon boundary layer profile was summarized. Then, the effects of typhoon horizontal structure, topography, wind speed, and time distance on the characteristics of the typhoon profile were discussed, respectively. Finally, the evolution characteristics of wind profile parameters were obtained by fitting three wind profile theoretical models. Due to the strong variability of typhoon profile morphology, the theoretical model of wind profile is only applicable to the wind profile from the bottom to the low-level jet height of typhoons, while wind parameters are closely related to the spatial location of the typhoon wind field. Full article

The present-day climate (the recent 100–150 years) obviously constitutes the structure of a global intra-system rhythmic process with an individual rhythm of about 60 years. In turn, each of the rhythms is presented by the two climate phases of about 25–35 years characterized by qualitative differences: one phase is relatively continental, while the other is humid. Globality and quasi-synchronism of environmental changes are accompanied by planetary structures: the Global Atmospheric Oscillation (GAO) in the atmosphere and the Multidecadal Oscillation of the Heat content in the Ocean (MOHO) discovered relatively recently. Unexpected and rapid qualitative phase changes in the climate, which first focused attention in the mid-1970s of the last century, were titled “climate shifts”. The revealed features of the present-day climate are of exceptional scientific and practical interest and deserve the development of methods for predicting the timing of the forthcoming climate shift. Arising unexpectedly and accompanied by rapid significant changes, these shifts identified the problem of understanding the nature and establishing the processes and mechanisms causing them. First of all, of interest are phase changes in the thermodynamic state of the climate system components: the ocean, atmosphere, and continents. As a result of the World Ocean (WO) thermohydrodynamics numerical modelling, it is shown that MOHO is localized in the layer of the main thermocline, where the most important elements of the WO circulation are located. The performed study based on observational data allows us to conclude that, during the phase of the WO thermal discharge (1975–1999), the two key systems of currents, the Kuroshio and the Gulf Stream, were under similar thermodynamic conditions. Full article

Triboelectric nanogenerators (TENGs) are an attractive energy harvesting technology due to their high efficiency and vast applications in self-powered sensors. In this work, dielectric–dielectric contact-separation TENGs were modeled with time-dependent finite element simulations with the objective of improving TENG’s performance by enhancing the relative permittivity (${\epsilon }_r$).To achieve this, the chosen material (PDMS, ${\epsilon }_r=2.75$) was doped with SrTiO${}_3$ (${\epsilon }_r$ = 300) particles. The open-circuit voltage ($V_{OC}$) and short-circuit current ($I_{SC}$) remained constant as ${ϵ}_r$ increased, as predicted by existent models, but in contradiction with available experimental data. Thus, we introduced a charge correction model relating ${ϵ}_r$ and surface charge density, allowing us to observe an increase in TENG performance output ($V_{OC}$ and $I_{SC}$). This work shows that finite element simulations are suitable for better understanding and optimizing TENGs’ performance. Full article

The enzymatic reaction stage (ECS) of oolong tea processing plays an important role in the formation of the flavor quality of the oolong tea. To investigate the dynamic changes in the volatile and non-volatile components in the leaves of oolong tea during the ECS, metabolomic studies were carried out using the leaf samples collected at different stages of the ECS of Aijiao oolong tea. Out of the identified 306 non-volatile metabolites and 85 volatile metabolites, 159 non-volatile metabolites and 42 volatile metabolites were screened out as key differential metabolites for dynamic changes during the ECS. A multivariate statistical analysis on the key differential metabolites showed that the accumulations of most metabolites exhibited dynamic changes, while some amino acids, nucleosides, and organic acids accumulated significantly after turning-over treatment. The evolution characteristics of 27 key precursors or transformed VOCs during the ECS of Aijiao oolong tea were clarified, and it was found that the synthesis of aroma substances was mainly concentrated in lipids as precursors and glycosides as precursor pathways. The results revealed the dynamic changes in the flavor metabolites in the ECS during the processing of Aijiao oolong tea, which provided valuable information for the formation of the characteristic flavor of Aijiao oolong tea. Full article