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EPR study of enzymatic cleavage of side chains of water soluble polymers using spin-label as a leaving group

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It was confirmed by EPR that 4-amino-2,2,6,6--tetramethylpiperidine-N-oxyl (TEMP-NH2) is cleaved by chymotrypsin from 4-(N-glycyl-L-phenylalanyl)amino −2,2,6,6-tetramethylpiperidine-N-oxyl attached as a substrate with paramagnetic leaving group to the end of side chains of water soluble hydroxypropyl methacrylamide (HPMA) compolymers.

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References

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Authors and Affiliations

  1. Institute of Macromolecular Chemistry, Czechoslovak Academy of Sciences, 162 06, Prague 6, Czechoslovakia

    J. Labský, J. Pilař & J. Kálal

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  1. J. Labský
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  2. J. Pilař
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  3. J. Kálal
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Labský, J., Pilař, J. & Kálal, J. EPR study of enzymatic cleavage of side chains of water soluble polymers using spin-label as a leaving group. Polymer Bulletin 1, 585–591 (1979). https://doi.org/10.1007/BF00254135

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  • DOI: https://doi.org/10.1007/BF00254135

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