Abstract
A group of thirteen young soldiers was standardized for approximately thirty hours with rest time extending from 22 45 to 07 00; during their activity time they abstained from any unusual or strenuous activity and ate meals only at 08 30, 14 30 and 16 30. Each man was sampled at three-hour intervals throughout one 24-hour period; this involved the measurement of oral temperature, radial pulse, systolic and diastolic blood pressure, infraocular pressure and minute ventilation. In addition, a sample of blood and urine was collected at each time point and subsequently a total of 18 biochemical or other measurements were made on each sample of serum and 15 measurements on each sample of urine.
In addition, one year later another study was similarly performed on twelve men. In this instance oral temperature, radial pulse and blood pressure were determined, and, in addition, several psychological or behavioral tests also were made; these include: estimation of mood or vigor, eye-hand coordination, finger counting, ability to estimate time, random number addition and memory.
All data were analyzed by a computerized inferential statistical method which involved the fitting of a 24-hour cosine curve to the data by a method of least squares. A great majority of the many variables analyzed demonstrated a significant fit to a 24-hour cosine curve. From this same analysis, one was able to estimate three rhythmic parameters and their confidence intervals; these include: the acrophase timing, the amplitude and the mesor (over-all mean). The significance of these data relates to medical diagnosis and basic views of man's structure in time.
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Supported by grants from the United States Public Health Service (5-K6-GM-13,981) and by NASA (IGR-24-005-006).
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Kanabrocki, E.L., Scheving, L.E., Halberg, F. et al. Circadian variations in presumably healthy men under conditions of peace-time army reserve unit training. Space Life Sciences 4, 258–270 (1973). https://doi.org/10.1007/BF00924473
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DOI: https://doi.org/10.1007/BF00924473