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Alopecia in laboratory animals induced by a polyampholyte, polyethylene alanine

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Summary

Polyethylene alanine, a polyaminoacid, was found to induce a characteristic alopecia when administered topically or systemically to suckling mice, or newborn guinea-pigs or rabbits.

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Authors and Affiliations

  1. Rega Instituut, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000, Leuven

    E. De Clercq, J. Descamps, P. De Somer, C. Samyn & G. Smets

  2. Laboratorium voor Macromoleculaire en Organische Scheikunde, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3030, Heverlee, Belgium

    E. De Clercq, J. Descamps, P. De Somer, C. Samyn & G. Smets

Authors
  1. E. De Clercq
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  2. J. Descamps
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  3. P. De Somer
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  4. C. Samyn
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  5. G. Smets
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Additional information

Acknowledgments. The authors thank Dr C. Peeters, Dr M.J. Vanstapel and Prof. Dr V. Desmet for the histopathological examination of the skin biopsy specimens, and Dr K. Marien for helpful discussions.

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De Clercq, E., Descamps, J., De Somer, P. et al. Alopecia in laboratory animals induced by a polyampholyte, polyethylene alanine. Experientia 36, 1107–1108 (1980). https://doi.org/10.1007/BF01965997

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  • DOI: https://doi.org/10.1007/BF01965997

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