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Persistent and atypical lobules in the human breast may be precancerous

  • Anatomica, Histologica, Embryologica, Carcinologica
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Summary

Persistent human mammary lobules (PL) remaining after the menopause, and certain atypical lobules (ALA) are morphologically similar to the common preneoplastic hyperplastic alveolar nodule (HAN) of mice of strains having a high incidence of mammary carcinoma. This and other evidence suggest that like the HAN of mice human PL and ALA are precancerous.

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Authors and Affiliations

  1. Department of Pathology, School of Medicine, University of California, 95616, Davis, California, USA

    S. R. Wellings, H. M. Jensen & M. R. DeVault

Authors
  1. S. R. Wellings
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  2. H. M. Jensen
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  3. M. R. DeVault
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Additional information

This work was supported by a contract from the National Institutes of Health. PHS NOI-CB-43908, and funds from the Cancer Research Coordinating Committee, University of California.

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Wellings, S.R., Jensen, H.M. & DeVault, M.R. Persistent and atypical lobules in the human breast may be precancerous. Experientia 32, 1463–1465 (1976). https://doi.org/10.1007/BF01937436

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  • DOI: https://doi.org/10.1007/BF01937436

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