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A new approach to preparation and purification of colostrokinin from bovine colostrum

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Summary

A simple and rapid method is reported for preparation and partial purification of colostrokinin from bovine colostral whey. The active substance obtained at the described stage of purification appears to be a basic polypeptide of low molecular weight. This peptide proved to be undestroyed by pepsin, only partially by trypsin and completely by papain.

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Authors and Affiliations

  1. Laboratorio di Chimica degli Ormoni, Consiglio Nazionale delle Ricerche, via Mario Bianco 9, I-20131, Milano, Italy

    M. M. Casellato, G. Lugaro, P. Pasta, E. Manera, P. Ormas & C. Beretta

  2. Istituto di Farmacologia e Tossicologia Veterinaria, Università di Milano, via Viotti 3/5, I-20133, Milano, Italy

    M. M. Casellato, G. Lugaro, P. Pasta, E. Manera, P. Ormas & C. Beretta

Authors
  1. M. M. Casellato
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  2. G. Lugaro
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  3. P. Pasta
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  4. E. Manera
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  5. P. Ormas
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  6. C. Beretta
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Additional information

Acknowledgment. This research was partially supported by the Italian Ministry of Health.

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Casellato, M.M., Lugaro, G., Pasta, P. et al. A new approach to preparation and purification of colostrokinin from bovine colostrum. Experientia 33, 485–487 (1977). https://doi.org/10.1007/BF01922225

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  • DOI: https://doi.org/10.1007/BF01922225

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