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Dämpfung des Kältezitterns durch Pentobarbital und Pethidin bei Ratten

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Summary

In rats, shivering was induced by cooling. Shivering started at 36.6°C in unanaesthetized rats and at 36.0°C in animals with light pentobarbital anaesthesia (5 mg/kg i.V.). Pethidine (2 mg/kg) lowered the onset of shivering in unanaesthetized rats to 35.3 °C and in anaesthetized animals to 33.0°C. The results suggest that the effect of pethidine upon shivering is potentiated by pentobarbital.

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  1. Institut für Pharmakologie und Toxikologie der Universität des Saarlandes, Homburg, Deutschland

    H. Schäfer

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  1. H. Schäfer
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Schäfer, H. Dämpfung des Kältezitterns durch Pentobarbital und Pethidin bei Ratten. Experientia 22, 407–408 (1966). https://doi.org/10.1007/BF01901168

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  • DOI: https://doi.org/10.1007/BF01901168

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