Summary
Modeccin, the toxin ofAdenia digitata, agglutinates erythrocytes from several mammalian species. The haemagglutinating activity is enhanced by neuraminidase and is inhibited by galactose and by galactose-containing sugars.
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K. Refsnes, T. Haylett, K. Sandvig and S. Olsnes, Biochem. biophys. Res. Commun.79, 1176 (1977).
F. Stirpe, A. Gasperi-Campani, L. Barbieri, E. Lorenzoni, L. Montanaro, S. Sperti and E. Bonetti, FEBS Lett.85, 65 (1978).
S. Olsnes, T. Haylett and K. Refsnes, J. biol. Chem.253, 5069 (1978).
A. Gasperi-Campani, L. Barbieri, E. Lorenzoni, L. Montanaro, S. Sperti, E. Bonetti and F. Stirpe, Biochem. J.174, 491 (1978).
S. Olsnes and A. Pihl, in: Receptors and Recognition, ser. B, vol. 1, p. 129. Ed. P. Cuatrecasas. London 1977.
G.L. Nicolson and J. Blaustein, Biochem. biophys. Acta266, 543 (1972).
G.L. Nicolson, J. Blaustein and M.E. Etzler, Biochemistry13, 196 (1976).
S. Olsnes, K. Sandvig, K. Eiklid and A. Pihl, J. supramolec. Struct.9, 15 (1978).
G. Neri, M.C. Giuliano, S. Capetillo, E.B. Gilliam, D.C. Hixson and E.F. Walborg, Jr, Cancer Res.36, 263 (1976).
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Acknowledgment. This research was supported by grants from the Consiglio Nazionale delle Ricerche, Rome, and by the Pallotti's legacy for cancer research.
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Gasperi-Campani, A., Franceschi, C., Perino, G. et al. Haemagglutinating activity of modeccin. Experientia 35, 1086–1087 (1979). https://doi.org/10.1007/BF01949957
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DOI: https://doi.org/10.1007/BF01949957