Abstract
Examination of the frequencies of several loci controlling isozymes in three geographically distinct feral populations of mice showed the average animal to be heterozygous at 10.3% of his loci. There was no evidence for interaction between loci, nor any evidence for inbreeding in the populations. Thirty-nine inbred strains, including four newly derived ones, were also characterized for their alleles for as many as 16 polymorphic loci. Among these strains, variability is at least as great as in any single feral population, but probably less than that found among all feral populations of the species.
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This work was supported by NIH Research Grants GM-9966 and GM-07249 from the Division of General Medical Science, and by contracts AT(30-1)-1979 and AT(30-1)-3671 with the U.S. Atomic Energy Commission.
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Roderick, T.H., Ruddle, F.H., Chapman, V.M. et al. Biochemical polymorphisms in feral and inbred mice (Mus musculus). Biochem Genet 5, 457–466 (1971). https://doi.org/10.1007/BF00487135
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DOI: https://doi.org/10.1007/BF00487135