ExLibris header image
SFX Logo
Title: Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
Source:

Nature Structural & Molecular Biology [1545-9993] Thakur, Ashwani yr:2009


Collapse list of basic services Basic
Full text
Full text available via Nature
GO
Document delivery
Request document via Library/Bibliothek GO
Users interested in this article also expressed an interest in the following:
1. Katsuno, M. "Testosterone Reduction Prevents Phenotypic Expression in a Transgenic Mouse Model of Spinal and Bulbar Muscular Atrophy." Neuron 35.5 (2002): 843-854. Link to SFX for this item
2. O'Nuallain, B. "Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay." Methods in enzymology 413 (2006): 34-74. Link to SFX for this item
3. Landles, C. "Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease." The Journal of biological chemistry 285.12 (2010): 8808-8823. Link to Full Text for this item Link to SFX for this item
4. Ermak,, Gennady, G. "Regulator of Calcineurin (RCAN1-1L) Is Deficient in Huntington Disease and Protective against Mutant Huntingtin Toxicity in Vitro." The Journal of biological chemistry 284.18 (2009): 11845-11853. Link to Full Text for this item Link to SFX for this item
5. Bocharova, N. "Protein aggregation and neurodegeneration : Clues from a yeast model of Huntington's disease." Biochemistry 74.2 (2009): 231-234. Link to SFX for this item
6. Chevalier-Larsen, Erica S S. "Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy." The journal of neuroscience 24.20 (2004): 4778-86. Link to Full Text for this item Link to SFX for this item
7. Gipson, Theresa A. "Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis." RNA biology 10.11 (2013): 1647-1652. Link to Full Text for this item Link to SFX for this item
8. Taylor, Albert P. "Repeat expansion disease: progress and puzzles in disease pathogenesis." Nature Reviews. Genetics 11.4 (2010): 247-258. Link to SFX for this item
9. Ling-Bo Li; Zhenming Yu; Xiuyin Teng; Nancy M. Bon, Ling-Bo B. "RNA toxicity is a component of ataxin-3 degeneration in Drosophila." Nature 453.7198 (2008): 1107-11. Link to Full Text for this item Link to SFX for this item
10. LASPADA, A R R. "ANDROGEN RECEPTOR GENE-MUTATIONS IN X-LINKED SPINAL AND BULBAR MUSCULAR-ATROPHY." Nature 352.6330 (1991): 77-79. Link to Full Text for this item Link to SFX for this item
11. Mangiarini, L. "Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice." Cell 87.3 (1996): 493-506. Link to SFX for this item
12. Ross, Christopher A. "Huntington's disease: from molecular pathogenesis to clinical treatment." Lancet neurology 10.1 (2011): 83-98. Link to SFX for this item
13. Gu, X. "Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice." Neuron 64.6 (2009): 828-840. Link to SFX for this item
14. O'Nuallain, B. "Seeding specificity in amyloid growth induced by heterologous fibrils." The Journal of biological chemistry 279.17 (2004): 17490-17499. Link to SFX for this item
15. Caviston, Juliane P. "Huntingtin as an essential integrator of intracellular vesicular trafficking." Trends in cell biology 19.4 (2009): 147-155. Link to SFX for this item
16. Finkbeiner, S. "Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease." The Journal of biological chemistry 284.7 (2009): 4398-4403. Link to Full Text for this item Link to SFX for this item
17. Benítez-Burraco, A. "[Huntington's disease: molecular foundations and implications in the characterisation of the neuronal mechanisms responsible for linguistic processing]." Rev Neurol 48.2 (2009): 75-84. Link to SFX for this item
18. Casas, J. "C-reactive protein and coronary heart disease: a critical review." Journal of internal medicine 264.4 (2008): 295-314. Link to Full Text for this item Link to SFX for this item
19. Bhattacharyya, Anusri M M. "polyglutamine aggregation nucleation: thermodynamics of a highly unfavorable protein folding reaction." Proceedings of the National Academy of Sciences of the United States of America 102.43 (2005): 15400-5. Link to Full Text for this item Link to SFX for this item
20. Shen, Vincent K. "Coarse-grained strategy for modeling protein stability in concentrated solutions. II: Phase behavior." Biophysical journal 90.6 (2006): 1949-1960. Link to Full Text for this item Link to SFX for this item
View More...
View Less...
Select All Clear All

Expand list of advanced services Advanced