SFX by Ex Libris Inc.

Title:	A frameshift mutation in MC4R associated with dominantly inherited human obesity
Source:	Nature Genetics [1061-4036] Yeo, Giles S.H. yr:1998

Basic

Full text

Full text available via Nature

Year:

Volume:

Issue:

Start Page:

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Lubrano-Berthelier, C. "Molecular genetics of human obesity-associated MC4R mutations." Annals of the New York Academy of Sciences 994.1 (2003): 49-57.
description	2.	Bradley, A. "Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice." Cell 88.1 (1991): 693-702.
description	3.	O'Rahilly, Thomas A. "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase." Science 318.5855 (2007): 1469-72.
description	4.	Krude, H. "Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans." Nature genetics 19.2 (1998): 155-7.
description	5.	Nargund, Ravi P P. "Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity." Journal of medicinal chemistry 49.14 (2006): 4035-4043.
description	6.	Farooqi, I Sadaf S. "Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene." The New England journal of medicine 348.12 (2003): 1085-95.
description	7.	McCarthy, MI I. "A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity." Science 316.5826 (2007): 889-894.
description	8.	Hotta, Kikuko, K. "Variations in the FTO gene are associated with severe obesity in the Japanese." Journal of human genetics 53.6 (2008): 546-553.
description	9.	Dina, C. "Variation in FTO contributes to childhood obesity and severe adult obesity." Nature genetics 39.6 (2007): 724-6.
description	10.	Loos, Ruth F. "Common variants near MC4R are associated with fat mass, weight and risk of obesity." Nature genetics 40.6 (2008): 768-75.
description	11.	Kishi, T. "Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat." Journal of comparative neurology 457.3 (2003): 213-35.
description	12.	Graham, M. "Overexpression of Agrt leads to obesity in transgenic mice." Nature genetics 17.3 (1997): 273-4.
description	13.	YOSHIDA, H. "THE MURINE MUTATION OSTEOPETROSIS IS IN THE CODING REGION OF THE MACROPHAGE COLONY STIMULATING FACTOR GENE." Nature 345.6274 (1990): 442-444.
description	14.	Wardle, J. "Obesity-associated genetic variation in FTO is associated with diminished satiety." The Journal of clinical endocrinology and metabolism 93.9 (2008): 3640-3.
description	15.	Mergen M, M. "A novel melanocortin 4 receptor (MC4R) gene mutation associated with morbid obesity." The Journal of clinical endocrinology & metabolism 86.7 (2001): 3448-3451.
description	16.	Young, E. H. "The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals." International journal of obesity 31.9 (2007): 1437-1441.
description	17.	Stratigopoulos, G. "Regulation of Fto/Ftm gene expression in mice and humans." American journal of physiology. regulatory, integrative and comparative physiology 294.4 (2008): -96.
description	18.	NUNEZ, C. "Bioimpedance analysis: evaluation of leg-to-leg system based on pressure contact foot-pad electrodes." Medicine and science in sports and exercise 29.4 (1997): 524-531.
description	19.	Montague, S. "Congenital leptin deficiency is associated with severe early-onset obesity in humans." Nature 387.6636: 903-908.
description	20.	Okuyama, S. "Involvement of melanocortin-4 receptor in anxiety and depression." Peptides 26.10 (2005): 1952-1964.