The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
MICROBIAL O-CARBAMYLATION OF NOVOBIOCIN
M. S. KUOD. A. YUREKD. G. CHIRBYJ. I. CIALDELLAV. P. MARSHALL
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JOURNAL FREE ACCESS

1991 Volume 44 Issue 10 Pages 1096-1100

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Abstract

Novobiocin was inactivated by Streptomyces niveus US 2094 in fermentation. The inactivation product was isolated and characterized by NMR and MS as 2"-O-carbamylnovobiocin. The MICs of novobiocin and 2"-O-carbamylnovobiocin were determined for S. niveus strains.

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© Japan Antibiotics Research Association
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